Xie Hui, Zhu Da-hui
Clifford Hospital, Guangzhou University of Chinese Medicine, Guangzhou 511495, China.
Zhongguo Zhong Yao Za Zhi. 2012 Sep;37(17):2505-9.
Salidroside is an extract from Rhodiola crenulata as well as one of major active constituents. In studies of recent years, salidroside showed multiple effects in protecting nerves, scavenging free radicals, regulating central nervous system neurotransmitter, increasing the ability to promote nerve repair and modulating of apoptosis-related gene expression. Hence, it is expected to be applied in treating degenerative nerve diseases and brain ischemic diseases. This essay summarizes studies on pharmacological effects of salidroside on nerve system diseases, providing reference for further studies, development and application of R. crenulata.
红景天苷是从大花红景天中提取的一种成分,也是其主要活性成分之一。近年来的研究表明,红景天苷在保护神经、清除自由基、调节中枢神经系统神经递质、增强促进神经修复能力以及调节凋亡相关基因表达等方面具有多种作用。因此,有望将其应用于治疗退行性神经疾病和脑缺血性疾病。本文综述了红景天苷对神经系统疾病药理作用的研究,为大花红景天的进一步研究、开发和应用提供参考。