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红景天苷对神经系统疾病药理作用的研究进展

[Advance in studies on pharmacological effect of salidroside on nervous system diseases].

作者信息

Xie Hui, Zhu Da-hui

机构信息

Clifford Hospital, Guangzhou University of Chinese Medicine, Guangzhou 511495, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2012 Sep;37(17):2505-9.

PMID:23236741
Abstract

Salidroside is an extract from Rhodiola crenulata as well as one of major active constituents. In studies of recent years, salidroside showed multiple effects in protecting nerves, scavenging free radicals, regulating central nervous system neurotransmitter, increasing the ability to promote nerve repair and modulating of apoptosis-related gene expression. Hence, it is expected to be applied in treating degenerative nerve diseases and brain ischemic diseases. This essay summarizes studies on pharmacological effects of salidroside on nerve system diseases, providing reference for further studies, development and application of R. crenulata.

摘要

红景天苷是从大花红景天中提取的一种成分,也是其主要活性成分之一。近年来的研究表明,红景天苷在保护神经、清除自由基、调节中枢神经系统神经递质、增强促进神经修复能力以及调节凋亡相关基因表达等方面具有多种作用。因此,有望将其应用于治疗退行性神经疾病和脑缺血性疾病。本文综述了红景天苷对神经系统疾病药理作用的研究,为大花红景天的进一步研究、开发和应用提供参考。

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1
[Advance in studies on pharmacological effect of salidroside on nervous system diseases].红景天苷对神经系统疾病药理作用的研究进展
Zhongguo Zhong Yao Za Zhi. 2012 Sep;37(17):2505-9.
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[Simultaneously preparation of grams of high purity tyrosol, crenulatin and salidroside from Rhodiola crenulata].[同时从大花红景天中制备克级高纯度酪醇、红景天黄素和红景天苷]
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Mechanism of action of Rhodiola, salidroside, tyrosol and triandrin in isolated neuroglial cells: an interactive pathway analysis of the downstream effects using RNA microarray data.红景天、红景天苷、酪醇和三萜醇在分离的神经胶质细胞中的作用机制:利用RNA微阵列数据对下游效应进行交互通路分析
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Salidroside orchestrates metabolic reprogramming by regulating the Hif-1α signalling pathway in acute mountain sickness.红景天苷通过调控急性高原病中的 Hif-1α 信号通路来调控代谢重编程。
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[Study on the extraction process for salidroside and p-tyrosol in Rhodiola crenulata].[大花红景天中红景天苷和对酪醇提取工艺的研究]
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Simultaneous Preparation of Salidroside and -Tyrosol from by DIAION HP-20 Macroporous Resin Chromatography Combined with Silica Gel Chromatography.大孔树脂 DIAION HP-20 与硅胶柱色谱联用同时从中制备红景天苷和酪醇。
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[Inhibitory effects of Rhodiola plants and their oligomeric proanthocyanidins on tyrosinase and Abeta42 aggregation].[红景天植物及其低聚原花青素对酪氨酸酶和β淀粉样蛋白42聚集的抑制作用]
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Salidroside: A review of its recent advances in synthetic pathways and pharmacological properties.红景天苷:对其合成途径和药理性质最新进展的综述。
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[Study on preparation of salidroside and polysaccharide in Rhodiola crenulata].[大花红景天中红景天苷和多糖的制备研究]
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[Purification of salidroside in Rhodiola crenulata with macroporous resin].[大孔树脂纯化藏药红景天中红景天苷的研究]
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