Going J J, Anderson T J, Crocker P R, Levison D A
Department of Pathology, University Medical School, Edinburgh, UK.
Histopathology. 1990 Feb;16(2):119-24. doi: 10.1111/j.1365-2559.1990.tb01079.x.
Breast tissue obtained from 18 of 246 women (7.3%) having localization biopsy for microcalcification contained crystals of Weddellite (calcium oxalate dihydrate). This was characterized by microscopic infra-red spectroscopy in three cases. Weddellite calcification was associated with benign lesions in 16 cases, but incidental atypical lobular hyperplasia and lobular carcinoma in situ were present, each in one case. Pathologists should be aware of this common non-haematoxyphilic, birefringent form of breast micro-calcification. Its presence has implications for the examination of biopsy specimens resulting from breast cancer screening using mammography.
在246名因微钙化接受定位活检的女性中，有18名（7.3%）的乳腺组织含有水草酸钙（二水合草酸钙）晶体。其中3例通过显微红外光谱对其进行了表征。16例水草酸钙钙化与良性病变相关，但各有1例伴有偶然的非典型小叶增生和小叶原位癌。病理学家应了解这种常见的非嗜苏木精、双折射性的乳腺微钙化形式。其存在对乳腺钼靶筛查导致的活检标本检查具有重要意义。
