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类风湿关节炎患者心血管危险因素识别与管理欠佳:一项队列分析

Suboptimal cardiovascular risk factor identification and management in patients with rheumatoid arthritis: a cohort analysis.

作者信息

Desai Shailey S, Myles James D, Kaplan Mariana J

出版信息

Arthritis Res Ther. 2012 Dec 13;14(6):R270. doi: 10.1186/ar4118.

Abstract

INTRODUCTION

Accelerated cardiovascular (CV) disease significantly contributes to increased mortality in rheumatoid arthritis (RA) patients, with a risk comparable to the one observed in patients with type 2 diabetes mellitus (DM). Part of this enhanced risk in RA is attributed to traditional cardiovascular risk factors (CRFs). The aims of this study were to determine how often traditional CRFs are identified and managed by (a) rheumatologists, compared with primary care physicians (PCPs) in RA patients; and (b) PCPs among patients with RA, DM, and the general population (GP).

METHODS

A retrospective cohort study compared age/gender/ethnicity-matched patients from three groups: RA, DM, and GP (without RA or DM); n = 251 patients per group. Electronic patient records were reviewed during a continuous 12-month period between June 2007 and April 2011 to assess whether CRFs were identified and managed.

RESULTS

In RA patients, PCPs managed obesity, BP, and lipids significantly more often than did rheumatologists. PCPs managed obesity, BP, and lipids significantly more often in diabetic patients than in the other two groups, and more often in the GP than in RA patients. In patients with elevated BMI, PCPs managed weight in 68% of the DM group, 46% of the GP, and 31% of the RA group (P < 0.0001 for all groups; P = 0.006 between RA and GP groups).

CONCLUSIONS

Rheumatologists identify and manage CRFs less frequently than PCPs. PCPs manage CRFs less frequently in RA patients, compared to the GP and DM. Given the increased CV risk associated with RA, physicians need to more aggressively manage CRFs in these patients.

摘要

引言

心血管疾病加速发展在类风湿关节炎(RA)患者死亡率增加中起显著作用,其风险与2型糖尿病(DM)患者相当。RA患者中这种风险增加的部分原因可归因于传统心血管危险因素(CRF)。本研究的目的是确定:(a)与RA患者的初级保健医生(PCP)相比,风湿科医生识别和管理传统CRF的频率;以及(b)RA患者、DM患者和普通人群(GP)中的PCP识别和管理传统CRF的频率。

方法

一项回顾性队列研究比较了三组年龄/性别/种族匹配的患者:RA组、DM组和GP组(无RA或DM);每组n = 251例患者。在2007年6月至2011年4月连续12个月期间对电子病历进行回顾,以评估是否识别和管理了CRF。

结果

在RA患者中,PCP管理肥胖、血压和血脂的频率显著高于风湿科医生。PCP管理糖尿病患者肥胖、血压和血脂的频率显著高于其他两组,管理普通人群的频率高于RA患者。在BMI升高的患者中,PCP管理体重的比例在DM组为68%,在GP组为46%,在RA组为31%(所有组P < 0.0001;RA组和GP组之间P = 0.006)。

结论

风湿科医生识别和管理CRF的频率低于PCP。与GP和DM相比,PCP管理RA患者CRF的频率较低。鉴于RA患者心血管风险增加,医生需要更积极地管理这些患者的CRF。

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