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类风湿关节炎患者对心血管风险评估指南的依从性较低:常规临床实践的回顾性病历审查

Low adherence to cardiovascular risk assessment guidelines in patients with rheumatoid arthritis: a retrospective chart review of routine clinical practice.

作者信息

Murphy Louise, Murphy Grainne, Cornally Nicola, McHugh Sheena, Saab Mohamad M, Cotter Patrick

机构信息

Catherine McAuley School of Nursing and Midwifery, University College Cork, Cork, T12 AK54, Ireland.

Department of Rheumatology, Cork University Hospital, Wilton, Cork, T12 DC4A, Ireland.

出版信息

Rheumatol Int. 2025 Jun 26;45(7):158. doi: 10.1007/s00296-025-05916-1.

Abstract

INTRODUCTION

Patients with rheumatoid arthritis (RA) have an elevated risk of developing cardiovascular disease (CVD). Despite European guidelines recommending routine CVD risk assessment, implementation in clinical practice is challenging. The objectives of this review were to determine if patients attending an Irish tertiary rheumatology centre received CVD risk assessments in line with European guidelines and assess the extent of CVD risk factor screening over five years of routine rheumatology care.

METHODS

A retrospective chart review was conducted for patients newly diagnosed with RA in 2018, with five-year follow-up. Data were extracted to determine if CVD risk assessments were performed, and where absent, risk was retrospectively calculated. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement checklist for cohort studies was used to guide the reporting of this study.

RESULTS

Among 21 patients, no documented CVD risk assessments were identified. CVD risk factor screening was consistently insufficient. There was a lack of documented clinical data necessary to conduct a CVD risk assessment on more than half of patients at study entry, and one quarter of patients at five-year follow up. Of those with data available (n = 10), retrospective calculations showed 80% had an undetected moderate or higher CVD risk at diagnosis. There was no documented referral to primary care for CVD risk assessment.

CONCLUSION

Implementation of CVD risk management guidelines in the routine care of patients with RA is challenging. The interpretation and operationalisation of guideline recommendations by rheumatology healthcare professionals in relation to implementation barriers needs to be explored.

摘要

引言

类风湿性关节炎(RA)患者患心血管疾病(CVD)的风险升高。尽管欧洲指南建议进行常规CVD风险评估,但在临床实践中实施具有挑战性。本综述的目的是确定在爱尔兰一家三级风湿病中心就诊的患者是否按照欧洲指南接受了CVD风险评估,并评估在五年的常规风湿病护理中CVD风险因素筛查的程度。

方法

对2018年新诊断为RA的患者进行回顾性病历审查,并进行五年随访。提取数据以确定是否进行了CVD风险评估,若未进行,则进行回顾性风险计算。采用队列研究的加强流行病学观察性研究报告(STROBE)声明清单来指导本研究的报告。

结果

在21名患者中,未发现有记录的CVD风险评估。CVD风险因素筛查一直不足。在研究开始时,超过一半的患者以及五年随访时四分之一的患者缺乏进行CVD风险评估所需的记录临床数据。在有可用数据的患者中(n = 10),回顾性计算显示80%的患者在诊断时存在未被发现的中度或更高CVD风险。没有记录显示因CVD风险评估而转诊至初级保健机构。

结论

在RA患者的常规护理中实施CVD风险管理指南具有挑战性。需要探索风湿病医疗专业人员对指南建议在实施障碍方面的解释和操作方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9708/12202671/b1f1638e55fb/296_2025_5916_Fig1_HTML.jpg

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