犬新孢子虫在实验感染牛体内的组织分布
Tissue distribution of Neospora caninum in experimentally infected cattle.
作者信息
Nishimura Maki, Kohara Junko, Hiasa Jun, Muroi Yoshikage, Yokoyama Naoaki, Kida Katsuya, Xuan Xuenan, Furuoka Hidefumi, Nishikawa Yoshifumi
机构信息
National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.
出版信息
Clin Vaccine Immunol. 2013 Feb;20(2):309-12. doi: 10.1128/CVI.00556-12. Epub 2012 Dec 12.
Abstract
Histopathology and quantitative PCR (qPCR) were used to determine the tissue distribution of Neospora caninum in calves at 80 days postinfection. Our findings revealed that the most appropriate brain areas for researching N. caninum pathogenesis were the amygdala and hippocampus for qPCR and the corpus striatum and diencephalon for histopathology.
摘要
组织病理学和定量聚合酶链反应（qPCR）被用于确定犊牛在感染后80天时犬新孢子虫的组织分布。我们的研究结果显示，用于研究犬新孢子虫发病机制的最合适脑区，对于qPCR而言是杏仁核和海马体，对于组织病理学而言是纹状体和间脑。
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