Scott Eirwen M, Smith Ashlee L, Desouki Mohamed Mokhtar, Olawaiye Alexander B
Department of Gynecologic Oncology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA.
Case Rep Obstet Gynecol. 2012;2012:862472. doi: 10.1155/2012/862472. Epub 2012 Dec 2.
Epithelioid trophoblastic tumor (ETT) is a rare gestational trophoblastic tumor. Cases of ETT present as abnormal vaginal bleeding in women of reproductive age, with low human chorionic gonadotropin (hCG) levels. ETT can be a sequela of any gestational event and can present in both intrauterine and extrauterine sites. Metastasis and death have been reported. We present a case of a 44-year-old female incidentally diagnosed with ETT following laparoscopic-assisted vaginal hysterectomy. Postoperative evaluation for metastatic disease was negative. The patient has been closely followed and remains disease free 8 months postoperatively. ETT presents a diagnostic challenge due to its rarity and histologic resemblance to other pathologies. ETT is relatively chemoresistant and managed surgically. Misdiagnosis delays effective treatment and affects survival.
上皮样滋养细胞肿瘤(ETT)是一种罕见的妊娠滋养细胞肿瘤。ETT病例表现为育龄期女性阴道异常出血,人绒毛膜促性腺激素(hCG)水平较低。ETT可能是任何妊娠事件的后遗症,可发生于子宫内和子宫外部位。已有转移和死亡的报道。我们报告一例44岁女性,在腹腔镜辅助下阴道子宫切除术后偶然诊断为ETT。术后转移性疾病评估为阴性。患者一直密切随访,术后8个月无疾病复发。由于ETT罕见且组织学上与其他病理相似性,其诊断具有挑战性。ETT相对化疗耐药,以手术治疗为主。误诊会延误有效治疗并影响生存。