以人绒毛膜促性腺激素升高为主要表现的子宫上皮样滋养细胞肿瘤：病例报告
Uterine epithelioid trophoblastic tumor with the main manifestation of increased human chorionic gonadotropin: A case report.
作者信息
Huang Li-Na, Deng Xi, Xu Jian
机构信息
Department of Gynecology, Ningbo Women and Children's Hospital, Ningbo 315012, Zhejiang Province, China.
Department of Ningbo Clinical Pathology Diagnosis Center, Ningbo 315021, Zhejiang Province, China.
出版信息
World J Clin Cases. 2024 Jun 6;12(16):2876-2880. doi: 10.12998/wjcc.v12.i16.2876.
BACKGROUND
Epithelioid trophoblastic tumor (ETT) is an extremely rare malignant gestational trophoblastic neoplasm commonly presenting with abnormal vaginal bleeding, abdominal pain, and increased human chorionic gonadotropin (hCG). This study reported a case of uterine ETT with the main manifestation being increased hCG.
CASE SUMMARY
A 39-year-old female was referred to the Ningbo Maternal and Child Hospital of China in December 2022, complaining of increased hCG levels for 1 month. Magnetic resonance imaging revealed gestational trophoblastic tumor, and hysteroscopic electrotomy and curettage of intrauterine hyperplasia were performed. The patient was diagnosed with uterine ETT through postoperative pathological examination and immunohistochemical results. Total laparoscopic hysterectomy and bilateral salpingectomy were performed, and hCG levels returned to normal. The patient was without recurrence during the postoperative 3-month follow-up.
CONCLUSION
This study reported a case of uterine ETT with the main manifestation being increased hCG, highlighting that ETT should be considered in the presence of abnormal hCG. A total laparoscopic hysterectomy is recommended.
背景
上皮样滋养细胞肿瘤（ETT）是一种极其罕见的恶性妊娠滋养细胞肿瘤，通常表现为异常阴道出血、腹痛和人绒毛膜促性腺激素（hCG）升高。本研究报告了一例以hCG升高为主要表现的子宫ETT病例。
病例摘要
一名39岁女性于2022年12月转诊至中国宁波市妇幼保健院，主诉hCG水平升高1个月。磁共振成像显示妊娠滋养细胞肿瘤，并进行了宫腔镜电切术和刮宫术以清除子宫内增生组织。通过术后病理检查和免疫组化结果，患者被诊断为子宫ETT。随后进行了全腹腔镜子宫切除术和双侧输卵管切除术，hCG水平恢复正常。术后3个月随访期间，患者无复发。
结论
本研究报告了一例以hCG升高为主要表现的子宫ETT病例，强调在hCG异常时应考虑ETT。建议行全腹腔镜子宫切除术。
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