Ehrenpreis E D, Lievens M W, Craig R M
Department of Medicine, Northwestern University Medical School, Chicago, Illinois.
J Clin Gastroenterol. 1990 Apr;12(2):188-9. doi: 10.1097/00004836-199004000-00015.
Although theoretically the spectrum of antimicrobial quinolone antibiotics are at low risk of producing Clostridium difficile overgrowth and diarrhea, a patient developed this clinical problem while receiving norfloxacin. We review the antimicrobial activity of the quinolone antibiotics, with respect to their predisposition for producing C. difficile-induced diarrhea.
虽然从理论上讲,喹诺酮类抗菌抗生素引发艰难梭菌过度生长和腹泻的风险较低,但有一名患者在接受诺氟沙星治疗时出现了这一临床问题。我们就喹诺酮类抗生素引发艰难梭菌所致腹泻的倾向,综述其抗菌活性。