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诺氟沙星治疗后艰难梭菌相关性腹泻

Clostridium difficile-associated diarrhea after norfloxacin.

作者信息

Ehrenpreis E D, Lievens M W, Craig R M

机构信息

Department of Medicine, Northwestern University Medical School, Chicago, Illinois.

出版信息

J Clin Gastroenterol. 1990 Apr;12(2):188-9. doi: 10.1097/00004836-199004000-00015.

DOI:10.1097/00004836-199004000-00015
PMID:2324482
Abstract

Although theoretically the spectrum of antimicrobial quinolone antibiotics are at low risk of producing Clostridium difficile overgrowth and diarrhea, a patient developed this clinical problem while receiving norfloxacin. We review the antimicrobial activity of the quinolone antibiotics, with respect to their predisposition for producing C. difficile-induced diarrhea.

摘要

虽然从理论上讲,喹诺酮类抗菌抗生素引发艰难梭菌过度生长和腹泻的风险较低,但有一名患者在接受诺氟沙星治疗时出现了这一临床问题。我们就喹诺酮类抗生素引发艰难梭菌所致腹泻的倾向,综述其抗菌活性。

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Clostridium difficile-associated diarrhea after norfloxacin.诺氟沙星治疗后艰难梭菌相关性腹泻
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引用本文的文献

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Tolerability of fluoroquinolone antibiotics. Past, present and future.氟喹诺酮类抗生素的耐受性:过去、现在与未来
Drug Saf. 1995 Dec;13(6):343-58. doi: 10.2165/00002018-199513060-00004.
2
Impact of the fluoroquinolones on gastrointestinal flora.氟喹诺酮类药物对胃肠道菌群的影响。
Drugs. 1993;45 Suppl 3:125-33. doi: 10.2165/00003495-199300453-00021.