Mastro T D, Spika J S, Lozano P, Appel J, Facklam R R
Division of Bacterial Diseases, Centers for Disease Control, Atlanta, GA 30333.
J Infect Dis. 1990 May;161(5):956-60. doi: 10.1093/infdis/161.5.956.
Pediococci, vancomycin-resistant gram-positive cocci, have been isolated from human specimens, but an association with clinical illness has not been established. Clinical and epidemiologic data were obtained on nine patients who had Pediococcus acidilactici isolated from blood. Patients were eight elderly adults with complicated medical problems and one infant with congenital jejunoileal atresia. Seven patients were hospitalized before P. acidilactici was isolated. Eight had received multiple antibiotics; however, only two had received vancomycin. In all cases there was a delay in correct bacterial identification, and the significance of the isolate was uncertain. There was no clearly identified syndrome associated with P. acidilactici bacteremia. All eight adults had fever and six had pneumonia potentially attributable to other causes. The findings underscore the importance of proper identification of vancomycin-resistant gram-positive cocci. P. acidilactici may be an opportunistic pathogen in severely compromised hosts; however, further observations are necessary to clarify its role in human disease.
从人类标本中分离出了耐万古霉素的革兰氏阳性球菌——片球菌，但尚未确定其与临床疾病的关联。我们获取了9例从血液中分离出嗜酸片球菌患者的临床和流行病学数据。患者包括8名患有复杂医疗问题的老年人和1名患有先天性空肠回肠闭锁的婴儿。7例患者在嗜酸片球菌分离前已住院。8例患者接受过多种抗生素治疗；然而，只有2例接受过万古霉素治疗。在所有病例中，正确的细菌鉴定均出现延迟，分离菌的意义尚不确定。没有明确确定与嗜酸片球菌菌血症相关的综合征。所有8名成年人都有发热，6人患有可能由其他原因引起的肺炎。这些发现强调了正确鉴定耐万古霉素革兰氏阳性球菌的重要性。嗜酸片球菌可能是严重受损宿主中的一种机会性病原体；然而，需要进一步观察以阐明其在人类疾病中的作用。
