Oakland University, School of Nursing, Rochester, MI, USA.
J Pediatr Nurs. 2013 May-Jun;28(3):258-66. doi: 10.1016/j.pedn.2012.11.003. Epub 2012 Dec 11.
Atherosclerosis is a global health issue beginning in childhood. Children's early development of cardiovascular disease (CVD) risk factors may include exposure to key biological components responsible for vascular inflammation in young adults. A retrospective medical record review based on the 2008 American Academy of Pediatrics childhood lipid screening recommendations examined current and initial CVD risk factors for 227 at-risk school-aged children during wellness exams to better determine the age when children are most likely to convert from being risk-free to at risk for CVD. An original risk trend algorithm analyzed risk clustering and risk trend progression. Risk onset was young (M=2.88 years), with family risk most prevalent and risk clustering and accumulation noted, perhaps precluding primordial prevention.
动脉粥样硬化是一个全球性的健康问题，从儿童期就开始了。儿童心血管疾病 (CVD) 风险因素的早期发展可能包括接触负责年轻人血管炎症的关键生物成分。一项基于 2008 年美国儿科学会儿童血脂筛查建议的回顾性病历审查，对 227 名处于危险中的学龄儿童进行了健康检查，以检查当前和初始 CVD 风险因素，以更好地确定儿童最有可能从无风险转变为 CVD 风险的年龄。原始风险趋势算法分析了风险聚类和风险趋势进展。风险开始得很早（M=2.88 岁），家族风险最为普遍，且存在风险聚类和积累，这可能排除了原始预防。
