Research Group Subcortical Contributions to Comprehension, Dept of Neuropsychology, Max Planck Institute of Human Cognition and Brain Science, Leipzig, Germany.
Biol Psychol. 2013 Feb;92(2):410-6. doi: 10.1016/j.biopsycho.2012.11.017. Epub 2012 Dec 14.
Sounds generated by one's own action elicit attenuated brain responses compared to brain responses to identical sounds that are externally-generated. The present study tested whether the suppression effect indexed by the N1- and P2-components of the event-related potential (ERP) is larger when self-generated sounds are correctly predicted than when they are not. Furthermore, sounds violating a prediction lead to a particular prediction error signal (i.e., N2b, P3a). Thus, we tested whether these error signals increase for self-generated sounds (i.e., enhanced N2b, P3a). We compared ERPs elicited by self- and externally-generated sounds that were of frequent standard and of infrequent deviant pitch. The results confirmed an N1- and P2-suppression effect elicited by self-generated standard sounds. The N1-suppression was smaller in response to self-initiated deviant sounds, indicating the specificity of predictions for self-generated sounds. In addition, an enhancement of N2b and P3a for self-generated deviants revealed the saliency of prediction error signals.
与外部产生的相同声音相比，人自身产生的声音会引起大脑反应减弱。本研究测试了当自我产生的声音被正确预测时，与当它们没有被正确预测时相比，事件相关电位（ERP）的 N1 和 P2 成分所标记的抑制效应是否更大。此外，违反预测的声音会导致特定的预测错误信号（即 N2b、P3a）。因此，我们测试了这些错误信号是否会随自我产生的声音而增加（即增强的 N2b、P3a）。我们比较了由自我产生和外部产生的声音诱发的 ERP，这些声音的频率标准和不频繁的偏差音高。结果证实了自我产生的标准声音引起的 N1 和 P2 抑制效应。自我产生的偏差声音引起的 N1 抑制作用较小，表明对自我产生的声音的预测具有特异性。此外，自我产生的偏差的 N2b 和 P3a 的增强揭示了预测误差信号的显著性。
