Preiss U, Ockert G, Brömme S, Otto A
Klinik und Poliklinik für Kinderheilkunde des Bereiches Medizin, Martin-Luther-Universität Halle-Wittenberg.
Klin Padiatr. 1990 Mar-Apr;202(2):120-3. doi: 10.1055/s-2007-1025503.
Clinical and laboratory findings of 123 paediatric patients with infections due to intestinal protozoa were analysed. Dientamoeba fragilis (D.f.) was found in 102 cases. The other patients had infections with Giardia lamblia or mixed infections with several other protozoa. Acute and recurrent diarrhoea were the most common findings (56 cases), whereas abdominal pain was more common in children with chronic symptoms. Peripheral eosinophilia was present in 32% of the children with dientamoebiasis. Metronidazole, oxytetracycline, doxycycline, and erythromycin were the most effective drugs in the treatment of D.f. infections. The therapy led coincidentally to the sanitation of stools and elimination of abdominal complaints. The investigations underline the pathogenic role of D.f. in those children with gastrointestinal symptoms. Mixed infections of D.f. and Enterobius vermicularis suggest a vector bound transmission of D.f.
对123例肠道原生动物感染的儿科患者的临床和实验室检查结果进行了分析。在102例患者中发现了脆弱双核阿米巴（D.f.）。其他患者感染了蓝氏贾第鞭毛虫或合并感染了其他几种原生动物。急性和复发性腹泻是最常见的症状（56例），而腹痛在有慢性症状的儿童中更为常见。32%的双核阿米巴病患儿外周血嗜酸性粒细胞增多。甲硝唑、土霉素、强力霉素和红霉素是治疗D.f.感染最有效的药物。该治疗同时使粪便卫生状况得到改善，并消除了腹部不适。这些研究强调了D.f.在有胃肠道症状儿童中的致病作用。D.f.与蠕形住肠线虫的混合感染提示D.f.存在媒介传播。
