Abbott Nutrition, Abbott Laboratories, 3300 Stelzer Road, Columbus, OH 43219, USA.
J Sci Food Agric. 2013 Jun;93(8):1945-52. doi: 10.1002/jsfa.5996. Epub 2012 Dec 18.
Human milk is the gold standard of infant nutrition and is a source of important substances, including carotenoids. Infant formulas are designed to mimic the composition and/or performance of human milk, although currently carotenoids are not routinely added to US infant formulas. The aim of this study was to assess plasma concentrations of β-carotene, lutein and lycopene 56 days after feeding infants milk-based infant formula without (CTRL) or with different concentrations of added carotenoids (L1 and L2).
Plasma carotenoid concentrations increased in infants fed carotenoid-supplemented formulas as compared with the control formula with no added carotenoids. At study day 56, infants fed the supplemented formulas (L1 and L2) had mean plasma lutein, β-carotene and lycopene concentrations that were within the range of a concurrent group of human milk-fed infants (HM). Anthropometric measurements were comparable among all study groups.
Plasma carotenoid concentrations of infants fed the supplemented formulas were within the range of the HM group and are consistent with reported plasma carotenoid ranges in human milk-fed infants. The experimental formulas were well tolerated and anthropometric measurements were comparable among all study groups.
母乳是婴儿营养的黄金标准，是包括类胡萝卜素在内的重要物质的来源。婴儿配方奶粉旨在模拟母乳的组成和/或性能，尽管目前在美国婴儿配方奶粉中通常不添加类胡萝卜素。本研究旨在评估喂养基于牛奶的婴儿配方奶粉的婴儿在 56 天后的血浆β-胡萝卜素、叶黄素和番茄红素浓度，这些配方奶粉不添加（CTRL）或添加不同浓度的类胡萝卜素（L1 和 L2）。
与未添加类胡萝卜素的对照配方相比，添加类胡萝卜素的配方可使喂养婴儿的血浆类胡萝卜素浓度增加。在研究第 56 天，喂养补充配方（L1 和 L2）的婴儿的血浆叶黄素、β-胡萝卜素和番茄红素浓度在同时期母乳喂养婴儿（HM）的范围内。所有研究组的人体测量指标相似。
喂养补充配方的婴儿的血浆类胡萝卜素浓度在 HM 组的范围内，与报告的母乳喂养婴儿的血浆类胡萝卜素范围一致。实验配方耐受性良好，所有研究组的人体测量指标相似。
