Ortega Candil Aída, Rodríguez Rey Cristina, Carreras Delgado José Luis
Department of Nuclear Medicine, Clinico San Carlos Hospital, 28040 Madrid, Spain.
ISRN Dermatol. 2012;2012:308279. doi: 10.5402/2012/308279. Epub 2012 Dec 4.
Nuclear medicine plays an essential role in the correct staging of patients suffering from melanoma. Both sentinel lymph node biopsy (SLNB) and positron emission tomography (PET) represent its main diagnostic tools. SLNB is the choice procedure for lymphatic regional staging of these patients, including the result of this technique in the 2002 American Joint Cancer Committee melanoma staging. SLNB sensitivity is superior than PET/CT for the detection of lymphatic micrometastases in early stages of the disease. PET/CT is mainly used in confirming clinical metastases suspected, detection of recurrences, and recurrence restaging. PET/CT has also shown superiority against conventional diagnostic methods in the detection of distant metastases, being able to detect illness even six months earlier than those methods.
核医学在黑色素瘤患者的正确分期中起着至关重要的作用。前哨淋巴结活检(SLNB)和正电子发射断层扫描(PET)是其主要诊断工具。SLNB是这些患者淋巴区域分期的首选方法,2002年美国癌症联合委员会黑色素瘤分期纳入了该技术的结果。在疾病早期检测淋巴微转移方面,SLNB的敏感性优于PET/CT。PET/CT主要用于确认疑似临床转移、检测复发以及复发再分期。在检测远处转移方面,PET/CT也显示出优于传统诊断方法的优势,甚至比那些方法能早六个月检测到疾病。