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孕期接种甲型H1N1流感疫苗后发生吉兰-巴雷综合征:孕晚期母婴护理——病例报告

Guillain-Barré Syndrome after H1N1 Shot in Pregnancy: Maternal and Fetal Care in the Third Trimester-Case Report.

作者信息

Campanharo Felipe Favorette, Santana Eduardo Felix Martins, Sarmento Stephanno Gomes Pereira, Mattar Rosiane, Sun Sue Yazaki, Moron Antonio Fernandes

机构信息

Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (UNIFESP), Alameda das Boninas, 299 Apartamento 112, Vila Mariana, 05303-000 São Paulo, SP, Brazil.

出版信息

Case Rep Obstet Gynecol. 2012;2012:323625. doi: 10.1155/2012/323625. Epub 2012 Dec 5.

Abstract

Guillain-Barré syndrome is a rare neurological disease of progressive installation, usually following a previous acute infectious state, has a rare incidence, especially in pregnancy, and can induce major complications and high mortality risk. Its occurrence, after immunization to influenza during the last trimester pregnancy, has not been reported before. We presented a case of a 36-year-old pregnant woman that was immunized to H1N1 in the last trimester; 10 days later she developed shoulder and lumbar spine's pain, limbs weakness and facial paralysis with unfavorable clinical evolution and was submitted to intensive therapy care. We described clinical and obstetrical approach, pointing out peculiarities involved in this pathology in pregnancy.

摘要

格林-巴利综合征是一种罕见的进行性神经系统疾病,通常继发于先前的急性感染状态,发病率很低,尤其是在妊娠期,可引发严重并发症及高死亡风险。此前尚未有关于在妊娠晚期接种流感疫苗后发生该疾病的报道。我们报告了一例36岁的孕妇,她在妊娠晚期接种了H1N1疫苗;10天后出现肩部和腰椎疼痛、肢体无力及面瘫,临床病情进展不利,随后接受了重症治疗护理。我们描述了临床及产科处理方法,指出了妊娠期该疾病所涉及的特殊情况。

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本文引用的文献

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Guillain-Barré syndrome in pregnancy.妊娠期格林-巴利综合征
Acta Obstet Gynecol Scand. 2004 Apr;83(4):319-25.
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Management of Landry-Guillain-Barré syndrome in pregnancy.
Obstet Gynecol. 1985 Mar;65(3 Suppl):25S-29S.
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The Guillain-Barré syndrome.吉兰-巴雷综合征
N Engl J Med. 1992 Apr 23;326(17):1130-6. doi: 10.1056/NEJM199204233261706.

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