Department of Occupational and Environmental Medicine, Institution of Medicine, Sahlgrenska Academy, University of Gothenburg, Box 414405 30, Gothenburg, Sweden.
BMC Public Health. 2012 Dec 21;12:1102. doi: 10.1186/1471-2458-12-1102.
This cross-sectional study explored relationships between psychosocial work environment, captured by job demand-control (JDC) and effort-reward imbalance (ERI), and seven cardiovascular heart disease (CHD) risk factors in a general population.
The sampled consists of randomly-selected men and women from Gothenburg, Sweden and the city's surrounding metropolitan areas. Associations between psychosocial variables and biomarkers were analysed with multiple linear regression adjusted for age, smoking, education and occupational status.
The study included 638 men and 668 women aged 24-71. Analysis between JDC and CHD risk factors illustrated that, for men, JDC was associated with impaired scores in several biomarkers, especially among those in high strain jobs. For women, there were no relationships between JDC and biomarkers. In the analysis of links between ERI and CHD risk factors, most associations tested null. The only findings were raised triglycerides and BMI among men in the fourth quartile of the ERI-ratio distribution, and lowered LDL-cholesterol for women. An complementary ERI analysis, combining high/low effort and reward into categories, illustrated lowered triglycerides and elevated HDL-cholesterol values among women reporting high efforts and high rewards, compared to women experiencing low effort and high reward.
There were some associations between psychosocial stressors and CHD risk factors. The cross-sectional design did not allow conclusions about causality but some results indicated gender differences regarding sensitivity to work stressors and also how the models might capture different psychosocial dimensions.
本横断面研究探讨了职业紧张模型(工作需求-控制模型和努力-回报失衡模型)中的心理社会工作环境与七种心血管疾病(CHD)风险因素之间的关系,该研究对象为来自瑞典哥德堡及其周边大都市区的随机选择的男性和女性。采用多元线性回归分析,调整了年龄、吸烟、教育程度和职业状况等因素后,分析了心理社会变量与生物标志物之间的关系。
本研究纳入了 638 名男性和 668 名年龄在 24-71 岁的女性。JDC 与 CHD 风险因素之间的分析表明,对于男性,JDC 与几种生物标志物的评分受损有关,尤其是在高压力工作中。对于女性,JDC 与生物标志物之间没有关系。在 ERI 与 CHD 风险因素之间关系的分析中,大多数检验结果为无效。唯一的发现是男性处于 ERI 比值分布第四四分位的人,甘油三酯和 BMI 升高,女性 LDL-胆固醇降低。对 ERI 的补充分析将高/低努力和回报结合成类别,表明报告高努力和高回报的女性的甘油三酯降低,HDL-胆固醇升高,而经历低努力和高回报的女性则相反。
心理社会应激源与 CHD 风险因素之间存在一些关联。横断面设计不允许得出关于因果关系的结论,但一些结果表明,性别差异与对工作应激源的敏感性有关,以及模型如何捕捉不同的心理社会维度。