Eriksson Peter, Schiöler Linus, Söderberg Mia, Rosengren Annika, Torén Kjell
Section of Occupational and Environmental Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Box 414, S-405 30, Gothenburg, Sweden.
Department of Molecular and Clinical Medicine, Su Sahlgrenska, 4135 45, Gothenburg, Sweden.
BMC Public Health. 2016 Mar 5;16:228. doi: 10.1186/s12889-016-2900-9.
Numerous studies have reported an association between stressing work conditions and cardiovascular disease. However, more evidence is needed, and the etiological mechanisms are unknown. Elevated resting heart rate has emerged as a possible risk factor for cardiovascular disease, but little is known about the relation to work-related stress. This study therefore investigated the association between job strain, job control, and job demands and resting heart rate.
We conducted a cross-sectional survey of randomly selected men and women in Västra Götalandsregionen, Sweden (West county of Sweden) (n = 1552). Information about job strain, job demands, job control, heart rate and covariates was collected during the period 2001-2004 as part of the INTERGENE/ADONIX research project. Six different linear regression models were used with adjustments for gender, age, BMI, smoking, education, and physical activity in the fully adjusted model. Job strain was operationalized as the log-transformed ratio of job demands over job control in the statistical analyses.
No associations were seen between resting heart rate and job demands. Job strain was associated with elevated resting heart rate in the unadjusted model (linear regression coefficient 1.26, 95 % CI 0.14 to 2.38), but not in any of the extended models. Low job control was associated with elevated resting heart rate after adjustments for gender, age, BMI, and smoking (linear regression coefficient -0.18, 95 % CI -0.30 to -0.02). However, there were no significant associations in the fully adjusted model.
Low job control and job strain, but not job demands, were associated with elevated resting heart rate. However, the observed associations were modest and may be explained by confounding effects.
众多研究报告了工作压力大与心血管疾病之间的关联。然而,仍需要更多证据,且病因机制尚不清楚。静息心率升高已成为心血管疾病的一个可能危险因素,但关于其与工作相关压力的关系知之甚少。因此,本研究调查了工作紧张、工作控制和工作需求与静息心率之间的关联。
我们对瑞典韦斯特罗斯兰地区(瑞典西部省份)随机抽取的男性和女性进行了横断面调查(n = 1552)。作为INTERGENE/ADONIX研究项目的一部分,在2001年至2004年期间收集了有关工作紧张、工作需求、工作控制、心率和协变量的信息。在完全调整模型中,使用了六种不同的线性回归模型,并对性别、年龄、体重指数、吸烟、教育程度和体育活动进行了调整。在统计分析中,工作紧张被定义为工作需求与工作控制的对数转换比值。
静息心率与工作需求之间未发现关联。在未调整模型中,工作紧张与静息心率升高相关(线性回归系数1.26,95%置信区间0.14至2.38),但在任何扩展模型中均无此关联。在对性别、年龄、体重指数和吸烟进行调整后,低工作控制与静息心率升高相关(线性回归系数 -0.18,95%置信区间 -0.30至 -0.02)。然而,在完全调整模型中没有显著关联。
低工作控制和工作紧张与静息心率升高相关,但工作需求与静息心率升高无关。然而,观察到的关联较小,可能是由混杂效应所解释。