Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg/Saar, Germany.
J Thorac Cardiovasc Surg. 2013 Mar;145(3 Suppl):S30-4. doi: 10.1016/j.jtcvs.2012.11.059. Epub 2012 Dec 20.
Repair of the bicuspid aortic valve may be performed in aortic regurgitation and aneurysm. Dilatation of the atrioventricular junction has been identified as a risk factor for repair failure, and we have used suture annuloplasty to correct atrioventricular junction enlargement. The objective was to compare the early results of aortic repair with and without annuloplasty.
Between November 1995 and January 12, a total of 559 patients were treated with bicuspid aortic valve repair for predominant regurgitation (n = 389), aortic aneurysm (n = 158), or acute dissection (n = 12). Isolated valve repair (aortic valve repair) was performed for aortic valve regurgitation with preserved aortic dimensions (n = 208) and sinotubular junction remodeling plus valve repair for aortic aneurysm and preserved root size (n = 116). Root remodeling was used for dilatation involving the root (n = 235). In 193 patients, dilatation of the atrioventricular junction (>27 mm) was corrected with suture annuloplasty.
Hospital mortality was 0.5% (n = 3); 2 patients required pacemaker implantation. Reoperation was necessary for recurrent regurgitation (n = 54) or stenosis (n = 2); 10-year freedom from reoperation was 82% but was inferior after isolated valve repair (70%, P = .007) compared with the 2 other techniques. Application of suture annuloplasty improved 3-year freedom from reoperation after isolated repair (84%) to 92% (P = .07). In all groups, the proportion of patients with no or trivial regurgitation was significantly higher with annuloplasty.
Preservation of the bicuspid aortic valve is feasible in many patients. Long-term stability of the repaired valves is good; the negative impact of a dilated atrioventricular junction can be reduced by suture annuloplasty.
在主动脉瓣关闭不全和主动脉瘤中,可以进行二叶式主动脉瓣修复。房室结扩张已被确定为修复失败的危险因素,我们使用缝线瓣环成形术来纠正房室结扩大。目的是比较主动脉瓣修复术和瓣环成形术的早期结果。
1995 年 11 月至 2006 年 1 月 12 日,共有 559 例患者因主要反流(n=389)、主动脉瘤(n=158)或急性夹层(n=12)接受了二叶式主动脉瓣修复术。主动脉瓣反流伴主动脉尺寸保留(n=208)行单纯瓣膜修复术,主动脉瘤和保留根部大小行窦管交界处重塑加瓣膜修复术(n=116)。对于涉及根部的扩张(n=235)采用根部重塑术。在 193 例患者中,房室结扩张(>27mm)通过缝线瓣环成形术进行校正。
院内死亡率为 0.5%(n=3);2 例患者需要植入起搏器。因复发性反流(n=54)或狭窄(n=2)需要再次手术;10 年无再手术率为 82%,但单纯瓣膜修复后较低(70%,P=0.007),与另外两种技术相比。在单纯修复术后,应用缝线瓣环成形术可提高 3 年无再手术率(84%)至 92%(P=0.07)。在所有组中,带瓣环成形术的患者无或轻微反流的比例显著更高。
在许多患者中,保留二叶式主动脉瓣是可行的。修复后的瓣膜长期稳定性良好;缝线瓣环成形术可降低扩张房室结的负面影响。