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疼痛门诊患者群体中药物转移的风险因素。

Risk factors for drug diversion in a pain clinic patient population.

作者信息

Walker Mary Jean, Webster Lynn R

机构信息

College of Nursing, University of Utah, Salt Lake City, UT, USA.

出版信息

J Opioid Manag. 2012 Nov-Dec;8(6):351-62. doi: 10.5055/jom.2012.0135.

Abstract

BACKGROUND

Prescription drug abuse and drug diversion have soared at the same time prescribing practices have increased, prompting the pain medicine community to seek more accurate knowledge of the sources of prescription drugs used non medically.

OBJECTIVE

To determine the extent of drug diversion and its risk factors in patients treated in a pain clinic.

METHODS

An anonymous patient survey was developed based on factors examined for their association with diversion identified from a literature search. Patients were asked to participate as they arrived for appointments at six chronic pain management clinics. Questions ascertained whether patients had experienced drug loss, theft, or diversion and, if so, the number of episodes. Data were analyzed to determine associations between identified risk factors and the following four identified ways of diverting prescription medications: stolen medications, lost medications, sharing of medications, and selling of medications. Data were also analyzed to determine the extent of drug diversion within the studied population.

RESULTS

Respondents had experienced a 45 percent incidence of some form of drug diversion on at least one occasion. The most common type of drug diversion was loss due to theft, reported by 30 percent of the respondents. Findings suggest family history of drug abuse and a history of criminal behavior can increase likelihood of drug diversion.

CONCLUSIONS

Drug diversion in a pain clinic population was common in this brief survey. Such diversion may contribute to the problems of nonmedical use of prescription drugs.

摘要

背景

在处方行为增加的同时,处方药滥用和药物转移现象激增,促使疼痛医学领域寻求对非医疗用途处方药来源的更准确认识。

目的

确定在疼痛诊所接受治疗的患者中药物转移的程度及其风险因素。

方法

基于从文献检索中确定的与药物转移相关的因素,开展了一项匿名患者调查。患者在前往六家慢性疼痛管理诊所预约就诊时被邀请参与。问题包括患者是否经历过药物丢失、被盗或转移,若有,发生次数。对数据进行分析,以确定已识别的风险因素与以下四种已识别的处方药转移方式之间的关联:药物被盗、药物丢失、药物共享和药物售卖。还对数据进行分析,以确定研究人群中药物转移的程度。

结果

受访者中至少有一次经历某种形式药物转移的发生率为45%。最常见的药物转移类型是因盗窃导致的丢失,30%的受访者报告了这一情况。研究结果表明,药物滥用家族史和犯罪行为史会增加药物转移的可能性。

结论

在这项简短调查中,疼痛诊所人群中的药物转移现象很常见。这种转移可能导致处方药非医疗使用的问题。

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