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医护人员中苯二氮䓬类药物的滥用:睡眠障碍对工作表现的影响。

Benzodiazepine Misuse Among Health Care Workers: The Effect of Sleep Disorders on Work Performance.

作者信息

Roncero Carlos, Bravo-Grande José Lorenzo, Andrés-Olivera Pilar, Peña Marta, Treceño Carlos, González-Pelaez Pilar, Aguilar Lourdes, Remón-Gallo Diego, González-Sánchez Armando

机构信息

Department of Health Sciences, Miguel de Cervantes European University (UEMC), Valladolid (Spain), C. del Padre Julio Chevalier, 2, 47012 Valladolid, Spain.

Instituto de Investigación Biomédica de Salamanca (IBSAL), Hospital Virgen de la Vega, 10 ª Planta, Paseo de San Vicente, 58-182, 37007 Salamanca, Spain.

出版信息

J Clin Med. 2025 Jun 16;14(12):4266. doi: 10.3390/jcm14124266.

DOI:10.3390/jcm14124266
PMID:40566012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12194565/
Abstract

: Benzodiazepines (BZDs), commonly used to treat insomnia and anxiety, are increasingly used in Spain, raising concerns due to their potential for abuse and dependence. This study investigates the use of BZDs and other psychotropic medications among healthcare workers, exploring their prevalence, associated factors, and their relationship with mental health issues following the COVID-19 pandemic. : An anonymous online survey was conducted among healthcare workers at the Salamanca University Healthcare Complex (CAUSA) from March 2023 to January 2024. Of 1121 participants, 685 provided complete responses, which were analysed. Insomnia, anxiety, and depression were assessed using the Insomnia Severity Index (ISI) and Patient Health Questionnaire-4 (PHQ-4). : Of the respondents, 23.8% reported using sleep medication, with 27.8% doing so without a prescription. Additionally, 14.7% used medication for depression or anxiety, with only 0.6% without a prescription. Hypnotic medicine use was associated with older age, insomnia, anxiety, depression, psychological or psychiatric treatment, COVID-19 after-effects, and diagnosed sleep disorders. Night-shift work was associated with increased hypnotic medication use in men but not in women. The use of these medications was linked to a reduced quality of life and impaired work performance. : The use of BZD and self-medication are prevalent among healthcare professionals, exceeding the rates observed in the general population. These findings highlight the urgent need for targeted interventions to address psychotropic medication use, promote other pharmacological and non-pharmacological alternatives for insomnia, and enhance mental health support for this vulnerable population.

摘要

苯二氮䓬类药物(BZDs)常用于治疗失眠和焦虑,在西班牙的使用越来越多,因其潜在的滥用和依赖可能性而引发担忧。本研究调查了医护人员中BZDs及其他精神药物的使用情况,探讨其流行程度、相关因素以及在2019冠状病毒病大流行后与心理健康问题的关系。:2023年3月至2024年1月,对萨拉曼卡大学医疗综合中心(CAUSA)的医护人员进行了一项匿名在线调查。在1121名参与者中,685人提供了完整回复并进行了分析。使用失眠严重程度指数(ISI)和患者健康问卷-4(PHQ-4)评估失眠、焦虑和抑郁情况。:在受访者中,23.8%报告使用助眠药物,其中27.8%是在没有处方的情况下使用。此外,14.7%使用治疗抑郁或焦虑的药物,只有0.6%是在没有处方的情况下使用。使用催眠药物与年龄较大、失眠、焦虑、抑郁、心理或精神治疗、2019冠状病毒病后遗症以及确诊的睡眠障碍有关。夜班工作与男性使用催眠药物增加有关,但与女性无关。使用这些药物与生活质量下降和工作表现受损有关。:BZD的使用和自我用药在医护人员中很普遍,超过了普通人群中的观察率。这些发现凸显了采取针对性干预措施以解决精神药物使用问题、推广其他治疗失眠的药物和非药物替代方法以及加强对这一弱势群体心理健康支持的迫切需求。

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本文引用的文献

1
Benzodiazepine use in Spain: risks and perspectives on the current situation and proposals for their rational use.西班牙苯二氮䓬类药物的使用:当前形势的风险与前景以及合理使用建议
Front Pharmacol. 2025 May 20;16:1547488. doi: 10.3389/fphar.2025.1547488. eCollection 2025.
2
The Relevance of Insomnia Among Healthcare Workers: A Post-Pandemic COVID-19 Analysis.医护人员中失眠问题的相关性:新冠疫情后的分析
J Clin Med. 2025 Feb 28;14(5):1663. doi: 10.3390/jcm14051663.
3
Unraveling the insomnia puzzle: sleep reactivity, attention deficit hyperactivity symptoms, and insomnia severity in ADHD Patients.
解开失眠之谜:多动症患者的睡眠反应性、注意力缺陷多动症状与失眠严重程度
Front Psychiatry. 2025 Jan 22;15:1528979. doi: 10.3389/fpsyt.2024.1528979. eCollection 2024.
4
Unravelling the myth: A cross-sectional study on coffee consumption among anesthesiologists in France.揭开谜团:法国麻醉师咖啡饮用情况的横断面研究。
Medicine (Baltimore). 2024 Nov 29;103(48):e40762. doi: 10.1097/MD.0000000000040762.
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An integrative systematic review of nurses' involvement in medication deprescription in long-term healthcare settings for older people.针对护士在老年人长期医疗保健环境中参与药物停用的综合系统评价。
Ther Adv Drug Saf. 2024 Oct 16;15:20420986241289205. doi: 10.1177/20420986241289205. eCollection 2024.
6
Stress, Mental Health, Sleep, and Healthy Habits in Spanish Healthcare Professionals Along the Pandemic: A Case-Control, and Follow-Up Study.西班牙医护人员在疫情期间的压力、心理健康、睡眠与健康习惯:一项病例对照及随访研究
Psychiatry Investig. 2024 May;21(5):487-495. doi: 10.30773/pi.2023.0368. Epub 2024 May 23.
7
Evaluation of the Association between Medication Use and Sleep Quality among Shift Workers versus Day Workers.轮班工人与日班工人用药与睡眠质量之间关联的评估。
Sleep Sci. 2024 Mar 26;17(1):e64-e74. doi: 10.1055/s-0043-1776743. eCollection 2024 Mar.
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"Multivariate analysis of the impact of sleep and working hours on medical errors: a MICE approach".“多变量分析睡眠和工作时间对医疗差错的影响:MICE 方法”。
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