利妥昔单抗可调节原发性干燥综合征患者唾液腺中白细胞介素-22的表达。 - Suppr

Rituximab modulates the expression of IL-22 in the salivary glands of patients with primary Sjogren's syndrome.

作者信息

Ciccia Francesco, Giardina Annarita, Rizzo Aroldo, Guggino Giuliana, Cipriani Paola, Carubbi Francesco, Giacomelli Roberto, Triolo Giovanni

出版信息

Ann Rheum Dis. 2013 May;72(5):782-3. doi: 10.1136/annrheumdis-2012-202754. Epub 2012 Dec 21.

DOI:10.1136/annrheumdis-2012-202754

PMID:23264342

Abstract

摘要

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Rituximab modulates the expression of IL-22 in the salivary glands of patients with primary Sjogren's syndrome.利妥昔单抗可调节原发性干燥综合征患者唾液腺中白细胞介素-22的表达。

Ann Rheum Dis. 2013 May;72(5):782-3. doi: 10.1136/annrheumdis-2012-202754. Epub 2012 Dec 21.

Rituximab modulates IL-17 expression in the salivary glands of patients with primary Sjögren's syndrome.利妥昔单抗调节原发性干燥综合征患者唾液腺中白细胞介素-17 的表达。

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NKp30 Receptor Upregulation in Salivary Glands of Sjögren's Syndrome Characterizes Ectopic Lymphoid Structures and Is Restricted by Rituximab Treatment.干燥综合征唾液腺中 NKp30 受体的上调特征性地表现为异位淋巴样结构，并受到利妥昔单抗治疗的限制。

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Blood and salivary-gland BAFF-driven B-cell hyperactivity is associated to rituximab inefficacy in primary Sjögren's syndrome.血液和唾液腺 BAFF 驱动的 B 细胞活性亢进与原发性干燥综合征中利妥昔单抗疗效不佳有关。

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Persistence of immunoglobulin-producing cells in parotid salivary glands of patients with primary Sjögren's syndrome after B cell depletion therapy.原发性干燥综合征患者 B 细胞耗竭治疗后腮腺中免疫球蛋白生成细胞的持续存在。

Ann Rheum Dis. 2012 Nov;71(11):1881-7. doi: 10.1136/annrheumdis-2011-201189. Epub 2012 May 21.

Efficacy and safety of rituximab treatment in early primary Sjögren's syndrome: a prospective, multi-center, follow-up study.利妥昔单抗治疗早期原发性干燥综合征的疗效和安全性：一项前瞻性、多中心、随访研究。

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Interleukin (IL)-17-producing pathogenic T lymphocytes co-express CD20 and are depleted by rituximab in primary Sjögren's syndrome: a pilot study.产生白细胞介素（IL）-17的致病性T淋巴细胞共表达CD20，且在原发性干燥综合征中可被利妥昔单抗清除：一项初步研究。

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Sjögren's syndrome: a quintessential B cell-induced autoimmune disease.干燥综合征：一种典型的B细胞诱导的自身免疫性疾病。

Joint Bone Spine. 2008 Jan;75(1):1-2. doi: 10.1016/j.jbspin.2007.07.001. Epub 2007 Aug 27.

First report of improvement of coeliac disease in a patient with Sjögren's syndrome treated with rituximab.利妥昔单抗治疗干燥综合征患者并发乳糜泻病情改善的首例报告。

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Int J Mol Sci. 2020 Dec 1;21(23):9172. doi: 10.3390/ijms21239172.

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Invariant NKT Cells and Rheumatic Disease: Focus on Primary Sjogren Syndrome.不变自然杀伤 T 细胞与风湿性疾病：以原发性干燥综合征为例。

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Interleukin-17 and -22 synergy linking inflammation and EMT-dependent fibrosis in Sjögren's syndrome.白细胞介素-17 和 -22 的协同作用将干燥综合征中的炎症与 EMT 依赖性纤维化联系起来。

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Rituximab modulates the expression of IL-22 in the salivary glands of patients with primary Sjogren's syndrome.

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