巴西圣保罗州鲍鲁市一只圈养蜘蛛猴体内亚马逊利什曼原虫的分子诊断
Molecular diagnosis of Leishmania amazonensis in a captive spider monkey in Bauru, São Paulo, Brazil.
作者信息
Lima Valéria Marçal Felix de, Santiago Maria Emília Bodini, Sanches Leticia da Cruz, Lima Beatriz Dolabela de
机构信息
Departamento de Clinica, Cirurgia e Reprodução Animal, Faculdade de Odontologia -- Medicina Veterinária, Universidade Estadual Paulista, Aragatuba, São Paulo, Brazil.
出版信息
J Zoo Wildl Med. 2012 Dec;43(4):943-5. doi: 10.1638/2012-0059R1.1.
The municipality of Bauru, São Paulo, Brazil, is an area endemic for leishmaniasis. At the zoo, a spider monkey (Ateles paniscus) showed nonpathognomonic symptoms, such as weight loss and pale mucous membranes. Blood was collected from the jugular vein and investigated for the presence of Leishmania spp. DNA by polymerase chain reaction and restriction fragment length polymorphism. Parasite DNA was detected, and the pattern observed was identical to Leishmania amazonensis. This study presents molecular evidence of L. amazonensis infection in a captive spider monkey.
巴西圣保罗州的鲍鲁市是利什曼病的地方性流行区。在动物园里，一只蜘蛛猴（Ateles paniscus）出现了非特异性症状，如体重减轻和黏膜苍白。从颈静脉采集血液，通过聚合酶链反应和限制性片段长度多态性检测利什曼原虫属DNA的存在。检测到了寄生虫DNA，观察到的模式与亚马逊利什曼原虫相同。本研究提供了圈养蜘蛛猴感染亚马逊利什曼原虫的分子证据。
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