Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, SP, Brazil.
Vector Borne Zoonotic Dis. 2011 May;11(5):593-4. doi: 10.1089/vbz.2010.0070. Epub 2010 Sep 16.
An adult female red-faced black spider monkey (Ateles paniscus), housed for 2 years in the Parque Estoril Zoo in São Paulo, Brazil, showed apathy. Clinical examination revealed discrete emaciation, swelling and induration of lymph nodes, and presence of a mass in the abdominal cavity. Therapies with enrofloxacin, azithromycin, and ceftiofur were ineffective. The animal died after 6 months. Necropsy and histopathology confirmed granulommas in lymph nodes, parietal and visceral pleura, lungs, liver, spleen, and kidneys. Acid-fast bacilli were isolated and identified as Mycobacterium tuberculosis by polymerase chain reaction restriction analysis and Spoligotyping techniques. The zoo personnel and other animals that had had contact with the infected primate were negative to tuberculosis diagnostic procedures, such as sputum exam (baciloscopy) and thorax radiography. It was impossible to determine whether the infection occurred before or after the arrival of the animal to the Parque Estoril Zoo. This is the first report of M. tuberculosis infection in Ateles paniscus, a neotropical primate.
一只 2 岁大的雌性红脸赤面蜘蛛猴（Ateles paniscus），饲养于巴西圣保罗的埃斯托里尔公园动物园，表现出冷漠。临床检查发现明显消瘦、淋巴结肿胀和硬结，以及腹腔内有肿块。用恩诺沙星、阿奇霉素和头孢噻呋治疗无效。该动物在 6 个月后死亡。尸检和组织病理学检查证实淋巴结、壁层和内脏胸膜、肺、肝、脾和肾有肉芽肿。通过聚合酶链反应限制分析和 spoligotyping 技术分离和鉴定出分枝杆菌结核。动物园工作人员和其他与受感染灵长类动物有过接触的动物对结核病诊断程序（如痰检（细菌镜检）和胸部 X 光检查）呈阴性。无法确定感染是在该动物到达埃斯托里尔公园动物园之前还是之后发生的。这是首例关于在新热带灵长类动物红脸赤面蜘蛛猴中感染结核分枝杆菌的报告。
