哮喘与犬弓首蛔虫感染之间的相关性。
Correlation between asthma and Toxocara canis infection.
作者信息
Cobzaru Roxana-Gabriela, Rîpă Carmen, Leon Maria Magdalena, Luca Mihaela Cătălina, Ivan A, Luca Mariana
机构信息
Discipline of Parasitology, University of Medicine and Pharmacy, Grigore T. Popa-Iasi School of Medicine.
出版信息
Rev Med Chir Soc Med Nat Iasi. 2012 Jul-Sep;116(3):727-30.
UNLABELLED
The aim of the current study was to examine the relationship between asthma and toxocariasis.
MATERIAL AND METHODS
We have studied 76 patients with asthma and 88 controls (without asthma) aged 5-16 years. An ELISA test based on the detection of anti-Toxocara canis (E/S antigen) serum immunoglobulin G (IgG) and E (IgE) was done in both groups. Ordinary allergens and E/S antigen of T. canis infections were used to evaluate cutaneous reactivity.
RESULTS
Seroprevalence in asthma patients was 68.42% and in the controls 13.63%. This difference was significant. The percentage of asthmatic patients with two anti-Toxocara antibodies was 26.31%, and of 4.54% in controls. All asthma patients with anti-Toxocara IgE had cutaneous reactivity to Ag E/S.
CONCLUSIONS
Asthma patients with anti-Toxocara IgE and IgG may have toxocariasis.
未标注
本研究的目的是探讨哮喘与弓蛔虫病之间的关系。
材料与方法
我们研究了76例年龄在5至16岁的哮喘患者和88例对照者（无哮喘）。两组均进行了基于检测抗犬弓蛔虫（E/S抗原）血清免疫球蛋白G（IgG）和E（IgE）的酶联免疫吸附测定（ELISA）试验。使用普通变应原和犬弓蛔虫感染的E/S抗原评估皮肤反应性。
结果
哮喘患者的血清阳性率为68.42%，对照者为13.63%。这一差异具有显著性。有两种抗弓蛔虫抗体的哮喘患者百分比为２6.31%，对照者为4.54%。所有抗弓蛔虫IgE的哮喘患者对Ag E/S均有皮肤反应性。
结论
具有抗弓蛔虫IgE和IgG的哮喘患者可能患有弓蛔虫病。
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