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我们使用纤维蛋白胶辅助植入 Ahmed 青光眼阀的经验。

Our experience of fibrin sealant-assisted implantation of Ahmed glaucoma valve.

机构信息

Department of Glaucoma, Jadhavbhai Nathamal Singhvi, Medical Research Foundation, Sankara Nethralaya, Chennai, India.

出版信息

Indian J Ophthalmol. 2013 Jan-Feb;61(1):23-7. doi: 10.4103/0301-4738.99976.

Abstract

AIM

To report our experience with the fibrin sealant as a suture substitute for securing the human scleral patch graft during implantation of Ahmed glaucoma valve (AGV).

MATERIALS AND METHODS

A retrospective, non-comparative study of 12 eyes of 12 patients who underwent an AGV implantation with fibrin sealant for part of the procedure during June 2009 to September 2010.

RESULTS

The mean patient age was 21.5 ± 20.6 years. Male: Female ratio was 2 : 1. Seven (58.3%) patients were monocular. The indications for AGV were varied. The mean number of intra-ocular surgeries prior to an implantation of AGV was 1.8. The mean follow-up duration was 24.5 ± 17.9 weeks. There was a statistically significant reduction in the mean IOP and in the mean number of anti-glaucoma medications at the final visit compared to the pre-operative values (P < 0.01, paired t test). Conjunctival retraction was seen in 1 (8.3%) case. The scleral patch graft was retracted posteriorly in another (8.3%) case. There was no case of AGV tube exposure, tube-cornea touch, or conjunctival erosion. Vision threatening complication viz. late post-operative rhegmatogenous retinal detachment, unlikely to be related to the use of the fibrin sealant, occurred in 2 (16.6%) eyes.

CONCLUSION

The fibrin sealant offers the advantages of safety and convenience to the placement of a scleral patch graft during an AGV implantation.

摘要

目的

报告我们使用纤维蛋白胶作为缝线替代物在 Ahmed 青光眼阀(AGV)植入术中固定人巩膜补丁移植物的经验。

材料和方法

回顾性、非对照研究 2009 年 6 月至 2010 年 9 月期间,12 例 12 只眼接受了纤维蛋白胶辅助的 AGV 植入术。

结果

患者平均年龄为 21.5 ± 20.6 岁。男女比例为 2:1。7 例(58.3%)为单眼。AGV 的适应证各不相同。植入 AGV 前平均眼内手术次数为 1.8 次。平均随访时间为 24.5 ± 17.9 周。与术前相比,最终随访时平均眼压和抗青光眼药物的平均数量均显著降低(P < 0.01,配对 t 检验)。1 例(8.3%)出现结膜退缩。另 1 例(8.3%)巩膜补丁移植物向后退缩。无 AGV 管暴露、管角膜接触或结膜侵蚀病例。2 只眼(16.6%)发生威胁视力的并发症,即晚期术后孔源性视网膜脱离,与使用纤维蛋白胶不太可能相关。

结论

纤维蛋白胶在 AGV 植入术中固定巩膜补丁移植物具有安全和方便的优点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30a1/3554990/80be67071def/IJO-61-23-g004.jpg

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