Shigemitsu T, Majima Y
Department of Ophthalmology, Fujita Health University School of Medicine, Fujita Health University, Aichi-Pref., Japan.
Int Ophthalmol. 1996;20(6):323-8. doi: 10.1007/BF00176885.
We produced a measurement apparatus for testing the tensile strength of wounds during cataract surgery, and tested the tensile strength of treated wounds including wounds sutured with various methods, non-sutured and wounds treated with various bio-tissue adhesives.
In cataract surgery on white rabbits eyes, a corneoscleral incision 5 mm in length was made 2.5 mm from the limbus corneae, and entry into the anterior chamber was obtained 0.5 mm to the clear cornea. After treatment for closure, the corneoscleral piece was subjected to the tensile strength test.
The tensile strengths just after surgery were (1) 0 gf/mm2 after self-sealing sutureless closure; (2) 114 gf/mm2 after vertical suture closure (one stitch with 10-0 nylon); (3) 125 gf/mm2 after horizontal suture closure (one stitch with 10-0 nylon); (4) 143 gf/mm2 after infinity suture closure (with 10-0 nylon); (5) 112 gf/mm2 after fibrin glue (Beriplast P) application (instilled on the surface of scleral incision); (6) 121 gf/mm2 after fibrin glue application (glued on corneoscleral wound); (7) 131 gf/mm2 after cyanoacrylate closure (instilled on the surface of scleral incision); (8) 139 gf/mm2 after cyanoacrylate closure (glued on corneoscleral wound). The respective strengths at four days after surgery were: (1) 86; (2) 131; (3) 137; (4) 175; (5) 109; (6) 43; (7) 138; and (8) 108 gf/mm2. At 28 days after surgery, the respective strengths were (1) 164; (2) 167; (3) 184; (4) 209; (5) 322; (6) 195; (7) 251; and (8) 175 gf/mm2.
The use of fibrin glue in treatment of a wound in cataract surgery is beneficial in assisting this treatment.
我们制作了一种用于测试白内障手术中伤口拉伸强度的测量装置，并测试了包括用各种方法缝合的伤口、未缝合的伤口以及用各种生物组织粘合剂处理的伤口在内的处理后伤口的拉伸强度。
在白兔眼的白内障手术中，在距角膜缘2.5毫米处制作一个5毫米长的角膜巩膜切口，并在透明角膜0.5毫米处进入前房。处理伤口闭合后，对角膜巩膜片进行拉伸强度测试。
手术后即刻的拉伸强度分别为：（1）自密封无缝合闭合后为0 gf/mm²；（2）垂直缝合闭合后（用10-0尼龙线缝一针）为114 gf/mm²；（3）水平缝合闭合后（用10-0尼龙线缝一针）为125 gf/mm²；（4）无限缝合闭合后（用10-0尼龙线）为143 gf/mm²；（5）应用纤维蛋白胶（Beriplast P）后（滴注在巩膜切口表面）为112 gf/mm²；（6）应用纤维蛋白胶后（粘贴在角膜巩膜伤口上）为121 gf/mm²；（7）应用氰基丙烯酸酯闭合后（滴注在巩膜切口表面）为131 gf/mm²；（8）应用氰基丙烯酸酯闭合后（粘贴在角膜巩膜伤口上）为139 gf/mm²。手术后四天的各自强度分别为：（1）86；（2）131；（3）137；（4）175；（5）109；（6）43；（7）138；（8）108 gf/mm²。手术后28天，各自强度分别为：（1）164；（2）167；（3）184；（4）209；（5）322；（6）195；（7）251；（8）175 gf/mm²。
在白内障手术伤口处理中使用纤维蛋白胶有助于该治疗。
