University of North Carolina at Chapel Hill, USA.
J Speech Lang Hear Res. 2013 Jun;56(3):891-905. doi: 10.1044/1092-4388(2012/12-0161). Epub 2012 Dec 28.
This study was conducted to evaluate the clinical utility of error variability for differentiating between apraxia of speech (AOS) and aphasia with phonemic paraphasia.
Participants were 32 individuals with aphasia after left cerebral injury. Diagnostic groups were formed on the basis of operationalized measures of recognized articulatory and prosodic characteristics of AOS and phonemic paraphasia. Sequential repetitions of multisyllabic words were elicited as part of a motor speech evaluation and transcribed phonetically. Four metrics of variability at the syllable and word levels were derived from these transcripts.
The measures yielded different magnitudes of variability. There were no group differences between participants who displayed speech profiles consistent with AOS and participants who displayed speech profiles indicative of aphasia with phonemic paraphasia. Rather, correlation coefficients and analyses of covariance showed that the variability metrics were significantly mediated by overall error rate. Additionally, variability scores for individuals with salient diagnoses of AOS and conduction aphasia were inconsistent with current diagnostic guidelines.
The results do not support diagnostic validity of error variability for differentiating between AOS and aphasia with phonemic paraphasia. Future research using error variability metrics should account for overall error rate in the analysis and matching of participant groups.
本研究旨在评估错误变异在区分构音障碍和有语音错语性失语症中的临床应用价值。
参与者为 32 名左脑损伤后患有失语症的个体。根据公认的构音障碍和语音错语性失语症的发音和韵律特征的操作性测量，形成了诊断组。多音节词的连续重复作为言语运动评估的一部分被引出，并进行了语音转录。从这些转写本中得出了音节和单词水平上的四个变异性度量。
这些措施产生了不同程度的变异性。在表现出与构音障碍一致的语音特征的参与者和表现出有语音错语性失语症的语音特征的参与者之间，没有组间差异。相反，相关系数和协方差分析表明，变异性度量受总错误率的显著影响。此外，具有明显构音障碍和传导性失语症诊断的个体的变异性得分与当前的诊断标准不一致。
结果不支持错误变异性在区分构音障碍和有语音错语性失语症中的诊断有效性。未来使用错误变异性度量的研究应在分析和匹配参与者组时考虑到总错误率。
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