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Disposition of primidone, phenylethylmalonamide, and phenobarbital in the rabbit.

作者信息

Hunt R J, Miller K W

出版信息

Drug Metab Dispos. 1978 Jan-Feb;6(1):75-81.

PMID:23277
Abstract
摘要

相似文献

1
Disposition of primidone, phenylethylmalonamide, and phenobarbital in the rabbit.
Drug Metab Dispos. 1978 Jan-Feb;6(1):75-81.
2
Serum concentrations of primidone and its metabolites, phenylethylmalonamide and phenobarbital, in the dog.犬体内扑米酮及其代谢产物苯乙基丙二酰胺和苯巴比妥的血清浓度。
Am J Vet Res. 1980 Oct;41(10):1643-5.
3
Placental transfer and pharmacokinetics of primidone and its metabolites phenobarbital, PEMA and hydroxyphenobarbital in neonates and infants of epileptic mothers.
Eur J Clin Pharmacol. 1980 Jul;18(1):31-42. doi: 10.1007/BF00561476.
4
Phenylethylmalonamide (PEMA). An important metabolite of primidone.
Arch Neurol. 1972 Jul;27(1):34-41. doi: 10.1001/archneur.1972.00490130036005.
5
Therapeutic serum concentrations of primidone and its metabolites, phenobarbital and phenylethylmalonamide in epileptic dogs.癫痫犬体内扑米酮及其代谢产物苯巴比妥和苯乙丙二酰胺的治疗血清浓度。
J Am Vet Med Assoc. 1983 May 15;182(10):1091-4.
6
The effects of phenytoin on phenobarbitone and primidone metabolism.苯妥英对苯巴比妥和扑米酮代谢的影响。
J Neurol Neurosurg Psychiatry. 1981 Feb;44(2):148-51. doi: 10.1136/jnnp.44.2.148.
7
Phenylethylmalonamide serum levels in patients treated with primidone and the effects of other antiepileptic drugs.
Ther Drug Monit. 1986;8(2):161-5. doi: 10.1097/00007691-198606000-00006.
8
Anticonvulsant effect of primidone in the gerbil. Time course and significance of the active metabolites.
Pharmacology. 1984;28(6):329-35. doi: 10.1159/000137981.
9
Isoniazid as an inhibitor of primidone metabolism.
Neurology. 1975 Dec;25(12):1179-81. doi: 10.1212/wnl.25.12.1179.
10
Phenytoin: an inhibitor and inducer of primidone metabolism in an epileptic patient.苯妥英：一名癫痫患者中扑米酮代谢的抑制剂和诱导剂。
Br J Clin Pharmacol. 1982 Aug;14(2):294-7. doi: 10.1111/j.1365-2125.1982.tb01980.x.

引用本文的文献

1
Blood and cerebrospinal fluid pharmacokinetics of primidone and its primary pharmacologically active metabolites, phenobarbital and phenylethylmalonamide in the rat.扑米酮及其主要药理活性代谢产物苯巴比妥和苯乙基丙二酰胺在大鼠体内的血液和脑脊液药代动力学
Eur J Drug Metab Pharmacokinet. 1999 Jul-Sep;24(3):255-64. doi: 10.1007/BF03190029.
2
Pharmacokinetics of phenylethylmalonamide (PEMA) after oral and intravenous administration.
Clin Pharmacokinet. 1983 May-Jun;8(3):272-6. doi: 10.2165/00003088-198308030-00006.