中国慢性阻塞性肺疾病患者的性别脆弱性。
Vulnerability of patients with chronic obstructive pulmonary disease according to gender in China.
机构信息
Xuzhou Center for Disease Control and Prevention, Affiliated Hospital of Xuzhou Medical College, Xuzhou City, Jiangsu Province, Xuzhou, China.
出版信息
Int J Chron Obstruct Pulmon Dis. 2012;7:825-32. doi: 10.2147/COPD.S37447. Epub 2012 Dec 20.
BACKGROUND
Little information is available regarding the vulnerability of patients with chronic obstructive pulmonary disease (COPD) in China. We aimed to assess this according to patient gender.
METHODS
A cross-sectional study was conducted in the rural area of Xuzhou in China. We interviewed and administered questionnaires to 2825 male and 2825 female patients with COPD and subjected the data generated to statistical analysis. We compared differences between proportions of male and female patients using the χ(2) test.
RESULTS
The rate of current smoking in men was 30.1%, whereas that in women was 10.9%, and 31.5% of men had a history of using biomass fuel compared with 75.3% of women. Further, 26.0% of the male patients and 16.4% of the female patients did not take theophylline regularly when their disease was stable. During acute exacerbations, 65.8% of the male patients and 39.7% of the female patients took theophylline or similar drugs. The average potential shortening of life expectancy was 1.76 years for men and 1.18 years for women. The average indirect economic burden was 11158.4 yuan for men and 7481.2 yuan for women. The quality of life was worse in female patients than in male patients.
CONCLUSION
We found that patients with COPD were vulnerable and that factors determining vulnerability were different for men than for women. Therefore, we recommend adopting different measures for men and women when attempting to prevent, control, and treat COPD, rehabilitate these patients, and improve their quality of life.
背景
关于中国慢性阻塞性肺疾病(COPD)患者的脆弱性,相关信息较少。我们旨在根据患者性别评估这一点。
方法
在中国徐州农村进行了一项横断面研究。我们对 2825 名男性和 2825 名女性 COPD 患者进行了访谈和问卷调查,并对生成的数据进行了统计分析。我们使用卡方检验比较了男性和女性患者比例之间的差异。
结果
男性当前吸烟率为 30.1%,而女性为 10.9%,31.5%的男性有使用生物质燃料的历史,而女性为 75.3%。此外,26.0%的男性患者和 16.4%的女性患者在病情稳定时没有规律地服用茶碱。在急性加重期,65.8%的男性患者和 39.7%的女性患者服用了茶碱或类似药物。男性预期寿命平均缩短 1.76 年,女性平均缩短 1.18 年。男性的平均间接经济负担为 11158.4 元,女性为 7481.2 元。女性患者的生活质量比男性患者差。
结论
我们发现 COPD 患者很脆弱,决定脆弱性的因素在男性和女性之间有所不同。因此,我们建议在试图预防、控制和治疗 COPD、康复这些患者并提高他们的生活质量时,对男性和女性采取不同的措施。