Department of Membrane Biochemistry, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
Physiology (Bethesda). 2013 Jan;28(1):39-50. doi: 10.1152/physiol.00033.2012.
Vesicular storage and subsequent release of neurotransmitters are the key processes of chemical signal transmission. In this process, vesicular neurotransmitter transporters are responsible for loading the signaling molecules. The use of a "clean biochemical" approach with purified, recombinant transporters has helped in the identification of novel vesicular neurotransmitter transporters and in the analysis of the control of signal transmission.
囊泡储存和随后的神经递质释放是化学信号传递的关键过程。在这个过程中，囊泡神经递质转运体负责装载信号分子。使用经过纯化和重组的转运体的“清洁生化”方法有助于识别新型囊泡神经递质转运体，并分析信号传递的控制。
