从白皮松中得到的具有独特的 5/11/5/6/5 环系和前所未有的双环[8.2.1]十三烷核的非典型的三萜内酯假海松烷酮。
Pseudolarenone, an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system featuring an unprecedented bicyclo[8.2.1]tridecane core from Pseudolarix amabilis.
机构信息
Department of Phytochemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, PR China.
出版信息
Chem Commun (Camb). 2013 Feb 11;49(12):1187-9. doi: 10.1039/c2cc37742j.
PMID:23282897
Abstract
A phytochemical investigation of the cone of Pseudolarix amabilis led to the isolation of pseudolarenone (), a structurally novel pentacyclic (5/11/5/6/5) nortriterpenoid lactone with an unprecedented carbon skeleton featuring a unique bicyclo[8.2.1]tridecane core. Its structure and absolute configurations were elucidated by spectroscopic analysis and single crystal X-ray diffraction (CuK(α)).
摘要
对白皮松球果的化学成分研究导致了伪白蜡素（）的分离，这是一种结构新颖的五环（5/11/5/6/5）倍半萜内酯，具有前所未有的碳骨架，具有独特的双环[8.2.1]十三烷核心。通过光谱分析和单晶 X 射线衍射（CuK(α)）确定了其结构和绝对构型。
相似文献
1
Pseudolarenone, an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system featuring an unprecedented bicyclo[8.2.1]tridecane core from Pseudolarix amabilis.
Chem Commun (Camb). 2013 Feb 11;49(12):1187-9. doi: 10.1039/c2cc37742j.
2
Pseudolaridimers A and B, hetero-cycloartane-labdane Diels-Alder adducts from the cone of Pseudolarix amabilis.
Org Lett. 2012 Nov 2;14(21):5432-5. doi: 10.1021/ol302501a. Epub 2012 Oct 17.
3
Biologically active dichapetalins from Dichapetalum gelonioides.
J Nat Prod. 2014 Apr 25;77(4):882-93. doi: 10.1021/np400971r. Epub 2014 Mar 5.
4
A novel eleven-membered-ring triterpene dilactone, pseudolarolide F and A related compound, pseudolarolide E, from Pseudolarix kaempferi.
J Asian Nat Prod Res. 2001;3(4):321-33. doi: 10.1080/10286020108040372.
5
Ainsliadimer A, a new sesquiterpene lactone dimer with an unusual carbon skeleton from Ainsliaea macrocephala.
Org Lett. 2008 Jun 19;10(12):2397-400. doi: 10.1021/ol800656q. Epub 2008 May 17.
6
Atranones A-G, from the toxigenic mold Stachybotrys chartarum.
Phytochemistry. 2000 Nov;55(6):663-73. doi: 10.1016/s0031-9422(00)00231-4.
7
Alstoscholactine and Alstolaxepine, Monoterpenoid Indole Alkaloids with γ-Lactone-Bridged Cycloheptane and Oxepane Moieties from Alstonia scholaris.
Org Lett. 2018 Dec 21;20(24):8014-8018. doi: 10.1021/acs.orglett.8b03592. Epub 2018 Dec 13.
8
Incarvilleatone, a new cyclohexylethanoid dimer from Incarvillea younghusbandii and its inhibition against nitric oxide (NO) release.
Org Lett. 2012 Apr 20;14(8):1954-7. doi: 10.1021/ol3004639. Epub 2012 Apr 6.
9
A pair of epimeric spirosesquiterpenes from the roots of Ligularia fischeri.
J Nat Prod. 2010 Feb 26;73(2):143-6. doi: 10.1021/np900492b.
10
Nortriterpene lactones from the fruits of Schisandra arisanensis.
J Nat Prod. 2010 Jul 23;73(7):1228-33. doi: 10.1021/np100048h.
引用本文的文献
1
3,4-Secocycloartane Triterpenoids from the Cones of Pseudolarix amabilis.
Nat Prod Bioprospect. 2021 Feb;11(1):119-126. doi: 10.1007/s13659-020-00285-7. Epub 2021 Jan 3.
Zotero 插件