急性播散性脑脊髓炎。MRI表现及与多发性硬化的鉴别
Acute disseminated encephalomyelitis. MRI findings and the distinction from multiple sclerosis.
作者信息
Kesselring J, Miller D H, Robb S A, Kendall B E, Moseley I F, Kingsley D, du Boulay E P, McDonald W I
机构信息
Multiple Sclerosis NMR Research Group, Institute of Neurology, Queen Square, London, UK.
出版信息
Brain. 1990 Apr;113 ( Pt 2):291-302. doi: 10.1093/brain/113.2.291.
Brain MRI was performed on 12 patients with acute disseminated encephalomyelitis (ADEM). Multifocal white matter lesions indistinguishable from those seen in multiple sclerosis (MS) were found in 10. In 5 there were rather extensive symmetric abnormalities in the cerebral (2) or cerebellar white matter (2), or basal ganglia (1). Follow-up MRI after intervals of 2 wks to 18 months demonstrated partial resolution of the abnormalities, but some persisting lesions. New MRI lesions were found at follow-up in only 1 case after an interval of 2 wks. Serial MRI makes a useful contribution to the distinction between MS and ADEM.
对12例急性播散性脑脊髓炎（ADEM）患者进行了脑部磁共振成像（MRI）检查。10例患者发现了与多发性硬化症（MS）中所见难以区分的多灶性白质病变。5例患者在大脑白质（2例）、小脑白质（2例）或基底神经节（1例）出现了相当广泛的对称性异常。在2周至18个月的间隔后进行的随访MRI显示，异常情况部分得到缓解，但仍有一些持续性病变。仅1例患者在2周的间隔后随访时发现了新的MRI病变。系列MRI对MS和ADEM的鉴别诊断有很大帮助。
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