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Perinatal Mortality Associated with Positive Postmortem Cultures for Common Oral Flora.围产期死亡率与常见口腔菌群尸检培养阳性相关
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本文引用的文献

1
Periodontal disease and adverse pregnancy outcomes: a systematic review.牙周疾病与不良妊娠结局:一项系统评价
BJOG. 2006 Feb;113(2):135-43. doi: 10.1111/j.1471-0528.2005.00827.x.
2
Pregnancy and lactation.怀孕与哺乳期。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Jun;97(6):672-82. doi: 10.1016/j.tripleo.2004.02.002.
3
Oral health and pregnancy: a review.口腔健康与妊娠:综述
N Y State Dent J. 2004 Jan;70(1):40-4.
4
PERIODONTAL DISEASE IN PREGNANCY. I. PREVALENCE AND SEVERITY.妊娠期牙周病。I. 患病率与严重程度。
Acta Odontol Scand. 1963 Dec;21:533-51. doi: 10.3109/00016356309011240.
5
Influence of sex hormones on the periodontium.性激素对牙周组织的影响。
J Clin Periodontol. 2003 Aug;30(8):671-81. doi: 10.1034/j.1600-051x.2003.00055.x.
6
Effect of pregnancy on periodontal and dental health.妊娠对牙周和牙齿健康的影响。
Acta Odontol Scand. 2002 Oct;60(5):257-64. doi: 10.1080/00016350260248210.
7
Causation and pathogenesis of periodontal disease.牙周病的病因及发病机制。
Periodontol 2000. 2001;25:8-20. doi: 10.1034/j.1600-0757.2001.22250102.x.
8
Potential pathogenic mechanisms of periodontitis associated pregnancy complications.牙周炎相关妊娠并发症的潜在致病机制。
Ann Periodontol. 1998 Jul;3(1):233-50. doi: 10.1902/annals.1998.3.1.233.
9
Periodontal infection as a possible risk factor for preterm low birth weight.牙周感染作为早产低出生体重的一个可能风险因素。
J Periodontol. 1996 Oct;67(10 Suppl):1103-13. doi: 10.1902/jop.1996.67.10s.1103.
10
Oral health status related to subgingival bacterial flora and sex hormones in saliva during pregnancy.孕期口腔健康状况与唾液中龈下细菌菌群及性激素的关系。
Bull Tokyo Dent Coll. 1994 Aug;35(3):139-51.

与妊娠相关的口腔厌氧微生物菌群的变化

Variations in the oral anaerobic microbial flora in relation to pregnancy.

作者信息

Basavaraju Anuradha, Durga S Vijaya, Vanitha B

机构信息

Professor, Department of Microbiology, Mamata Medical College, Khammam, Andhra Pradesh, India.

出版信息

J Clin Diagn Res. 2012 Nov;6(9):1489-91. doi: 10.7860/JCDR/2012/4609.2540.

DOI:10.7860/JCDR/2012/4609.2540
PMID:23285437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3527777/
Abstract

INTRODUCTION

Pregnancy gingivitis is a major oral infection. Periodontium acts as a reservoir of inflammatory mediators and sub gingival biofilms of bacteria.

AIM

To evaluate the anaerobic oral microbial flora in pregnant women before delivery and after delivery by comparing them with control group.

MATERIAL AND METHODS

The study group included fifteen cases of pregnant women before and after delivery and healthy non-pregnant women of same age as control group. Sub gingival plaque samples were collected with the help of dentists. The samples were inoculated immediately into Thioglycollate broth (MV010), transported to the laboratory, inoculated on to selective media for anaerobes (Hi-media laboratories) incubated anaerobically (Gas pack).

RESULTS

Prevotella, Tanerella forsythia, Porphyromonas gingivalis and Fusobacterium nucleatum, Veillonella, Peptostreptococcus were isolated.

DISCUSSION

The anaerobic bacteria in pregnant women were Prevotella, Tanerella forsythia and Porphyromonas gingivalis. Viellonella and Peptostreptococcus were seen in control group and after delivery. Research suggests that periodontal pathogens may travel the blood stream from the oral cavity to the placenta.

CONCLUSION

Pregnancy has significant effect on periodontal tissue. There is a significant alteration of bacterial flora during and after pregnancy. Oral health has to become a part of antenatal care /check up.

摘要

引言

妊娠龈炎是一种主要的口腔感染。牙周组织是炎症介质和龈下细菌生物膜的储存库。

目的

通过与对照组比较,评估孕妇分娩前和分娩后的口腔厌氧微生物菌群。

材料与方法

研究组包括15例分娩前后的孕妇以及与对照组年龄相同的健康未孕女性。在牙医的帮助下采集龈下菌斑样本。样本立即接种到硫乙醇酸盐肉汤(MV010)中,运送到实验室,接种到厌氧菌选择性培养基(Hi-media实验室)上,进行厌氧培养(气体发生袋)。

结果

分离出普氏菌属、福赛坦氏菌、牙龈卟啉单胞菌、具核梭杆菌、韦荣氏菌属、消化链球菌。

讨论

孕妇中的厌氧菌为普氏菌属、福赛坦氏菌和牙龈卟啉单胞菌。韦荣氏菌属和消化链球菌在对照组及分娩后可见。研究表明,牙周病原体可能从口腔经血流到达胎盘。

结论

妊娠对牙周组织有显著影响。妊娠期间及产后细菌菌群有显著改变。口腔健康必须成为产前护理/检查的一部分。