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δ-氨基乙酰丙酸合成酶和δ-氨基乙酰丙酸脱水酶在虹鳟(Salmo gairdnerii)肝脏和肾脏中的分布

Distribution of delta-aminolevulinic acid synthetase and delta-aminolevulinic acid dehydratase in liver and kidney of rainbow trout (Salmo gairdnerii).

作者信息

Addison R F, Fitzpatrick D, Renton K W

机构信息

Department of Fisheries and Oceans, Bedford Institute of Oceanography, Dartmouth, N.S., Canada.

出版信息

Comp Biochem Physiol B. 1990;95(2):317-9. doi: 10.1016/0305-0491(90)90082-5.

DOI:10.1016/0305-0491(90)90082-5
PMID:2328569
Abstract
  1. Activities of delta-aminolevulinic acid synthetase (ALA-S) and delta-aminolevulinic acid dehydratase (ALA-D) in trout liver and kidney were compared with those in the mouse. 2. ALA-S activity (per unit tissue fresh weight) exceeded ALA-D activity in trout liver and kidney. 3. In trout kidney, ALA-S activity slightly exceeded, and ALA-D activity far exceeded, their activities in trout liver. 4. In trout, heme synthesis differs from that in mammals in that appreciable synthesis occurs in the kidney, and in that ALA-S activity is not rate limiting.
摘要
  1. 将虹鳟鱼肝和肾中δ-氨基乙酰丙酸合成酶(ALA-S)及δ-氨基乙酰丙酸脱水酶(ALA-D)的活性与小鼠中的进行了比较。2. 虹鳟鱼肝和肾中ALA-S的活性(每单位组织鲜重)超过了ALA-D的活性。3. 在虹鳟肾中,ALA-S的活性略高于其肝中的活性,而ALA-D的活性则远高于其肝中的活性。4. 在虹鳟中,血红素的合成与哺乳动物不同,在于其肾脏中会发生可观的合成,且ALA-S的活性不是限速因素。

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