Antibodies to glutamate reduce the neurotoxic effects of Aβ(25-35) in prefrontal cortex cell transcriptome.

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作者信息

Kolobov V V, Fomina V G, Davydova T V

机构信息

Research Center for Neurology, Russian Academy of Medical Sciences, Volokolamskoe sh. 80, Moscow, 125367, Russia.

出版信息

Dokl Biochem Biophys. 2012 Nov-Dec;447:277-9. doi: 10.1134/S1607672912050092. Epub 2013 Jan 4.

DOI:10.1134/S1607672912050092

PMID:23288567

Abstract

摘要

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Beta-amyloid activates PARP causing astrocytic metabolic failure and neuronal death.β-淀粉样蛋白激活 PARP，导致星形胶质细胞代谢衰竭和神经元死亡。

Brain. 2011 Jun;134(Pt 6):1658-72. doi: 10.1093/brain/awr104.

Antiamnestic effects of antibodies to glutamate in experimental Alzheimer's disease.实验性阿尔茨海默病中谷氨酸抗体的抗遗忘作用

Bull Exp Biol Med. 2010 Dec;150(1):23-5. doi: 10.1007/s10517-010-1058-1.

Interactions between cognition and circadian rhythms: attentional demands modify circadian entrainment.认知与昼夜节律之间的相互作用：注意力需求会改变昼夜节律的同步。

Behav Neurosci. 2009 Oct;123(5):937-48. doi: 10.1037/a0017128.

Production of autoantibodies to glutamate during Alzheimer's dementia.阿尔茨海默病性痴呆期间谷氨酸自身抗体的产生。

Bull Exp Biol Med. 2009 Apr;147(4):405-7. doi: 10.1007/s10517-009-0530-2.

Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.使用实时定量PCR和2(-ΔΔC(T))方法分析相对基因表达数据。

Methods. 2001 Dec;25(4):402-8. doi: 10.1006/meth.2001.1262.

beta-amyloid neurotoxicity is mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis.β-淀粉样蛋白神经毒性由大鼠基底核中谷氨酸触发的兴奋性毒性级联反应介导。

Eur J Neurosci. 2000 Aug;12(8):2735-45. doi: 10.1046/j.1460-9568.2000.00164.x.

Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.线粒体锰超氧化物歧化酶可预防神经细胞凋亡并减轻缺血性脑损伤：抑制过氧亚硝酸盐生成、脂质过氧化及线粒体功能障碍。

J Neurosci. 1998 Jan 15;18(2):687-97. doi: 10.1523/JNEUROSCI.18-02-00687.1998.

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis.DFF是一种异二聚体蛋白，在细胞凋亡过程中，它在半胱天冬酶-3下游发挥作用，触发DNA片段化。

Cell. 1997 Apr 18;89(2):175-84. doi: 10.1016/s0092-8674(00)80197-x.

Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease.人类中枢神经系统内吞体-溶酶体系统的特性：功能紊乱在阿尔茨海默病中标记了大多数有退化风险的神经元群体。

J Neurosci. 1996 Jan;16(1):186-99. doi: 10.1523/JNEUROSCI.16-01-00186.1996.

Antibodies against gamma-aminobutyric acid: specificity studies and immunocytochemical results.抗γ-氨基丁酸抗体：特异性研究及免疫细胞化学结果

Proc Natl Acad Sci U S A. 1984 Jun;81(12):3888-92. doi: 10.1073/pnas.81.12.3888.

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