Xie Xiao-liang, Xing Yan, Li Jue, Hu Da-yi
Center for Cardiovascular and Pulmonary Blood Vessel, Tongji University, Shanghai 200092, China.
Zhonghua Nei Ke Za Zhi. 2012 Oct;51(10):774-6.
To investigate epidemiological characteristics and differences in ankle-brachial index (ABI) among the natural population in Shanghai and Inner Mongolia, and to observe the prevalence of lower extremity peripheral arterial disease (PAD).
A total of 2604 volunteers from Shanghai and Inner Mongolia were selected by stratified cluster random sample. ABI was measured and related data were collected.
The ABI value in Shanghai was 1.074 ± 0.095, while it was 1.062 ± 0.075 in Inner Mongolia (P < 0.001). The prevalence of lower extremity PAD in Shanghai was 4.2%, while it was 1.9% in Inner Mongolia (P < 0.01). For males, the ABI value in Shanghai was 1.078 ± 0.105, and it was 1.075 ± 0.080 in Inner Mongolia (P > 0.05). For females, the ABI value in Shanghai was 1.073 ± 0.089, while it was 1.052 ± 0.070 in Inner Mongolia (P < 0.001). For males, the prevalence of lower extremity PAD of the in Shanghai was 4.7%, while it was 2.0% in Inner Mongolia (P < 0.05). For females, the prevalence of lower extremity PAD of in Shanghai was 4.0%, while it was 1.8% in Inner Mongolia (P < 0.05). The ABI values in age group of < 50 years in Shanghai and Inner Mongolia were 1.037 ± 0.082 and 1.055 ± 0.068, respectively (P < 0.05). The prevalences of lower extremity PAD in age group of < 50 years in Shanghai and Inner Mongolia were 7.6% and 1.2%, respectively (P < 0.001). There were no significant differences in ABI value and the prevalence of lower extremity PAD between Shanghai and Inner Mongolia in both age group of 50 - 69 years and ≥ 70 years (all P values > 0.05).
The ABI value in Shanghai is higher than that in Inner Mongolia and the prevalence of lower extremity PAD in both males and females in Shanghai is significantly higher than that in Inner Mongolia. But they are lower than the level of western countries. In different age groups, the difference of the prevalence of lower extremity PAD between Shanghai and Inner Mongolia is only displayed in the age group of < 50 years, which may be related to the limited sample size. The natural population in Shanghai exposed artery atherosclerotic disease risk factors may increase and we need to pay more attention to the lower extremity PAD.
探讨上海和内蒙古自然人群踝臂指数（ABI）的流行病学特征及差异，观察下肢外周动脉疾病（PAD）的患病率。
采用分层整群随机抽样法，选取上海和内蒙古的2604名志愿者。测量ABI并收集相关数据。
上海的ABI值为1.074±0.095，内蒙古为1.062±0.075（P<0.001）。上海下肢PAD患病率为4.2%，内蒙古为1.9%（P<0.01）。男性中，上海的ABI值为1.078±0.105，内蒙古为1.075±0.080（P>0.05）。女性中，上海的ABI值为1.073±0.089，内蒙古为1.052±0.070（P<0.001）。男性中，上海下肢PAD患病率为4.7%，内蒙古为2.0%（P<0.05）。女性中，上海下肢PAD患病率为4.0%，内蒙古为1.8%（P<0.05）。上海和内蒙古<50岁年龄组的ABI值分别为1.037±0.082和1.055±0.068（P<0.05）。上海和内蒙古<50岁年龄组的下肢PAD患病率分别为7.6%和1.2%（P<0.001）。在50 - 69岁和≥70岁年龄组中，上海和内蒙古的ABI值及下肢PAD患病率均无显著差异（所有P值>0.05）。
上海的ABI值高于内蒙古，上海男性和女性下肢PAD的患病率均显著高于内蒙古。但均低于西方国家水平。在不同年龄组中，上海和内蒙古下肢PAD患病率的差异仅在<50岁年龄组中表现出来，这可能与样本量有限有关。上海自然人群暴露于动脉粥样硬化疾病危险因素的情况可能增加，我们需要更加关注下肢PAD。
