Wang Yong, Li Jue, Xu Ya-wei, Buaijiaer Ha-simu, Yang Jin-gang, Yuan Hong, Hu Da-yi
Heart, Lung and Blood Vessel Center, Tongji University, Shanghai 200092, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Dec;37(12):1127-31.
To investigate the prevalence of peripheral arterial disease (PAD) and correlative risk factors among natural population in China.
Ankle brachial index (ABI) was measured by trained doctors and related data were collected in residents from Beijing, Shanghai, Changsha, Guangdong, Neimenggu, and Xinjiang selected through cluster multistage and random sampling method. PAD was defined as an ABI < or = 0.9 in either leg.
The prevalence of PAD among 21 152 eligible participants was 3.08%, the standardized prevalence was 3.04%. The prevalence in males and females was 2.52% and 3.66% and the standardized prevalence was 1.84% and 4.31% respectively, the prevalence rate was significantly lower in males than that in females (P < 0.01). The prevalence in both males and females increased significantly in proportion to aging (P < 0.01). The prevalence in Han Chinese was significantly higher than that in non-Han Chinese (P < 0.01). Logistic regression analysis showed that older age, female gender, Han Chinese, waist circumference, smoking, lipid disorder, diabetes mellitus, coronary artery disease and a history of ischemic stroke were associated with the increased prevalence of PAD. Incidence of known PAD was 1.38% in this cohort.
Older age, female gender, Han Chinese, waist circumference, smoking, lipid disorder, diabetes mellitus, coronary artery disease and a history of ischemic stroke were associated with the increased prevalence of PAD in natural Chinese population.
调查中国自然人群外周动脉疾病(PAD)的患病率及其相关危险因素。
由经过培训的医生测量踝臂指数(ABI),并采用整群多级随机抽样方法收集来自北京、上海、长沙、广东、内蒙古和新疆居民的相关数据。PAD定义为任一腿部ABI≤0.9。
在21152名符合条件的参与者中,PAD的患病率为3.08%,标准化患病率为3.04%。男性和女性的患病率分别为2.52%和3.66%,标准化患病率分别为1.84%和4.31%,男性患病率显著低于女性(P<0.01)。男性和女性的患病率均随年龄增长而显著增加(P<0.01)。汉族人群的患病率显著高于非汉族人群(P<0.01)。Logistic回归分析显示,年龄较大、女性、汉族、腰围、吸烟、血脂异常、糖尿病、冠状动脉疾病和缺血性卒中病史与PAD患病率增加相关。该队列中已知PAD的发病率为1.38%。
年龄较大、女性、汉族、腰围、吸烟、血脂异常、糖尿病、冠状动脉疾病和缺血性卒中病史与中国自然人群PAD患病率增加相关。