Department of Mechanical Engineering, University of British Columbia, Vancouver, V6T 1Z4 BC, Canada.
IEEE Trans Biomed Eng. 2013 May;60(5):1431-8. doi: 10.1109/TBME.2012.2236326. Epub 2012 Dec 31.
We present a hand-held device aimed for reflectance-mode confocal imaging of biological tissues. The device consists of a light carrying optical fiber and a miniaturized raster scanner located at the distal end of the fiber. It is fabricated by mounting a polarization maintaining optical fiber on a cantilever beam that is attached to another beam such that their bending axes are perpendicular to each other. Fiber scanner is driven by electromagnetic forces and enables large fiber deflections with low driving currents. Optical resolutions of the system are 1.55 and 8.45 μm in the lateral and axial directions, respectively. Functionality of the system is demonstrated by obtaining confocal images of a fly wing and a human colon tissue sample.
我们展示了一种用于生物组织反射模式共焦成像的手持式设备。该设备由一根带有光纤的光载体和位于光纤远端的微型光栅扫描仪组成。它是通过将保偏光纤安装在悬臂梁上制成的,该悬臂梁连接到另一根梁上,使它们的弯曲轴彼此垂直。光纤扫描仪由电磁力驱动,能够以低驱动电流实现大光纤偏折。该系统的光学分辨率分别为横向 1.55μm 和轴向 8.45μm。通过获得蝇翅和人结肠组织样本的共焦图像,证明了该系统的功能。