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[心肾贫血综合征(综述)]

[Cardiorenal anemia syndrome (review)].

作者信息

Minasyan A

机构信息

Yerevan State Medical University after M. Heratsi, Yerevan, Armenia.

出版信息

Georgian Med News. 2012 Dec(213):17-21.

Abstract

Cardiorenal anemia syndrome (CRAS) refers to the simultaneous presence of anemia, heart failure (HF), and chronic kidney disease (CKD) that forms a pathologic triad with an observe impact on morbidity and mortality. Certain researches were made regarding the usage of erythropoietin (EPO) in patients with the above mentioned disorders. This leads to the improvement of left ventricular function, quality of life and physical tolerance with decreased risk of hospitalization. Despite successful anemia treatment with EPO in dialysis patients with CKD, HF and cardiorenal syndrome type 2, it should be important to reveal the target Hb level and role of EPO in this category of patients. According to European guidelines in 85% of hemodialysis patients targeted Hb level should be no more than 11g/dl, moreover, the treatment of anemia can be organized before dialysis and it will certainly increase the quality of life in this type of patients.

摘要

心肾贫血综合征(CRAS)指的是贫血、心力衰竭(HF)和慢性肾脏病(CKD)同时存在,它们形成了一个病理三联征,对发病率和死亡率有显著影响。针对上述疾病患者使用促红细胞生成素(EPO)进行了一些研究。这导致左心室功能、生活质量和身体耐受性得到改善,住院风险降低。尽管在患有CKD、HF和2型心肾综合征的透析患者中使用EPO成功治疗了贫血,但明确这类患者的目标血红蛋白水平以及EPO的作用仍很重要。根据欧洲指南,85%的血液透析患者的目标血红蛋白水平应不超过11g/dl,此外,贫血治疗可在透析前进行,这肯定会提高这类患者的生活质量。

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