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巴西基底细胞癌患者的生活质量:一项初步的横断面研究。

Quality of life in Basal cell carcinoma patients in Brazil: a pilot cross sectional study.

机构信息

Dermatology Service, Hospital Universitário, Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil.

出版信息

Dermatol Surg. 2013 Apr;39(4):620-6. doi: 10.1111/dsu.12098. Epub 2013 Jan 7.

Abstract

BACKGROUND

Basal cell carcinoma (BCC) is the most common malignant neoplasm in humans. BCC is asymptomatic, and its growth is slow, which may explain why patients often delay seeking treatment.

OBJECTIVE

To determine the clinical, historical, and demographic variables associated with the high Dermatology Life Quality Index (DLQI) scores of patients with BCC.

METHODS

We performed a cross-sectional study of 78 consecutive patients with primary BCCs who underwent tumor excision with margin control. Age, sex, habits, number of BCCs, BCC location, pathologic types, and DLQI were analyzed.

RESULTS

Most patients had skin phototypes I and II (89.8%) and nodular BCC (66.0%). DLQI analysis showed that 89.7% of patients had scores less than 5 (no or small effects on patient's life). Wearing sunscreen for more than 5 years, tumor ulceration, having a tumor larger than 2 cm in diameter, and having a tumor located not on the head were associated with higher DLQI scores in patients (p < .05).

CONCLUSION

Age, sex, outdoor activities, habitual sun exposure, or quantity of tumors did not influence quality of life. Patients who had used sunscreen for more than 5 years, had ulcerated tumors, had tumors larger than 2 cm and had tumors located outside of the head had higher DLQI scores.

摘要

背景

基底细胞癌(BCC)是人类最常见的恶性肿瘤。BCC 通常无症状且生长缓慢,这可能是患者经常延迟治疗的原因。

目的

确定与 BCC 患者高皮肤病生活质量指数(DLQI)评分相关的临床、既往史和人口统计学变量。

方法

我们对 78 例接受边缘控制的原发性 BCC 切除术的连续患者进行了横断面研究。分析了年龄、性别、习惯、BCC 数量、BCC 位置、病理类型和 DLQI。

结果

大多数患者的皮肤光型为 I 型和 II 型(89.8%)和结节型 BCC(66.0%)。DLQI 分析显示,89.7%的患者评分低于 5(对患者生活无或有较小影响)。患者接受防晒霜防护>5 年、肿瘤溃疡、肿瘤直径>2cm 以及肿瘤位于头部以外与更高的 DLQI 评分相关(p<.05)。

结论

年龄、性别、户外活动、习惯性日晒或肿瘤数量并不影响生活质量。使用防晒霜>5 年、肿瘤溃疡、肿瘤直径>2cm 以及肿瘤位于头部以外的患者具有更高的 DLQI 评分。

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