De Groot Veva, Hubert Mia, Van Best Jaap A, Engelen Sanne, Van Aelst Stefan, Tassignon Marie José
Department of Ophthalmology, University of Antwerp, Edegem, Belgium.
J Cataract Refract Surg. 2003 Dec;29(12):2330-8. doi: 10.1016/s0886-3350(03)00341-9.
To evaluate the integrity of the aqueous-vitreous barrier by assessing the flow of fluorescein from the anterior chamber to the anterior vitreous using fluorophotometry in eyes with a posterior continuous curvilinear capsulorhexis (PCCC) and in eyes without a PCCC.
University Hospital Antwerp, Edegem, Belgium.
Ten patients had bilateral extracapsular cataract extraction with implantation of an intraocular lens. In 1 eye, a PCCC was performed; the other eye served as a negative control. The eyes of 2 other patients who had complicated cataract surgery with posterior capsule and anterior hyaloid membrane rupture served as positive controls. All patients had fluorophotometry of both eyes 12 to 18 months after surgery to measure the flow of fluorescein from the anterior chamber to the anterior vitreous.
There were no statistically significant differences in the distribution pattern of fluorescein between eyes with PCCC and eyes without PCCC. In contrast, enhanced flow was detected in both eyes with rupture of the posterior capsule and the anterior hyaloid.
In this fluorophotometry study, a PCCC did not seem to disrupt the aqueous-vitreous barrier. Results indicate that an intact anterior vitreous membrane is crucial to maintain the barrier function between the anterior and the posterior segments of the eye.
通过使用荧光光度法评估荧光素从前房到玻璃体前部的流动情况，来评价具有后连续环形撕囊（PCCC）的眼和没有PCCC的眼中房水 - 玻璃体屏障的完整性。
比利时埃代海姆安特卫普大学医院。
10例患者接受了双侧囊外白内障摘除联合人工晶状体植入术。其中1只眼进行了PCCC；另一只眼作为阴性对照。另外2例白内障手术并发后囊膜和前玻璃体膜破裂的患者的眼作为阳性对照。所有患者在术后12至18个月对双眼进行荧光光度法检测，以测量荧光素从前房到玻璃体前部的流动情况。
有PCCC的眼和没有PCCC的眼之间荧光素的分布模式没有统计学上的显著差异。相比之下，在后囊膜和前玻璃体破裂的双眼均检测到荧光素流动增强。
在这项荧光光度法研究中，PCCC似乎并未破坏房水 - 玻璃体屏障。结果表明，完整的前玻璃体膜对于维持眼前后节之间的屏障功能至关重要。
