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纤维肉瘤的计算机断层扫描特征——猫注射部位肉瘤的一种组织学亚型

Computed tomography characteristics of fibrosarcoma -- a histological subtype of feline injection-site sarcoma.

作者信息

Travetti Olga, di Giancamillo Mauro, Stefanello Damiano, Ferrari Roberta, Giudice Chiara, Grieco Valeria, Saunders Jimmy H

机构信息

Department of Medical Imaging of Domestic Animals and Orthopedics of Small Animals, Ghent University, Belgium.

出版信息

J Feline Med Surg. 2013 Jun;15(6):488-93. doi: 10.1177/1098612X12472174. Epub 2013 Jan 7.

Abstract

Feline injection-site sarcoma (FISS) may be a consequence of subcutaneous injection. In the present study, the medical records and the computed tomography (CT) features of 22 cats with a FISS, histopathological subtype fibrosarcoma, were used. The majority of the fibrosarcomas (45%) were located in the interscapular region. All fibrosarcomas, except one with mild enhancement, showed strong contrast uptake, characterised as ring (42%), heterogeneous (36%), homogeneous (9%), heterogeneous/ring (6.5%) or mixed heterogeneous/homogeneous enhancement (6.5%). The longest axis of the mass was in a cranio-caudal (68%) or dorso-ventral (32%) direction. The median volume calculated on CT was 7.57 cm(3). Common features were a marked local invasiveness of the musculature and heterogeneity of the tissue in the periphery of the neoplasia. When the fibrosarcoma was interscapular, performing an additional post-contrast scan with the forelimbs positioned caudally along the body, in addition to the standard protocol with the forelimbs extended cranially, allowed better evaluation of the actual relationship between the tumour and the surrounding tissues. The mean number of muscles involved with the tumour was 2.09 with extended and 1.95 with flexed forelimbs. When a lower number of structures was considered infiltrated through the double positioning, a less invasive surgical approach to underlying muscles and scapula was performed.

摘要

猫注射部位肉瘤(FISS)可能是皮下注射的结果。在本研究中,使用了22只患有FISS(组织病理学亚型为纤维肉瘤)的猫的病历和计算机断层扫描(CT)特征。大多数纤维肉瘤(45%)位于肩胛间区域。除1例轻度强化外,所有纤维肉瘤均表现为强烈的对比剂摄取,表现为环形(42%)、不均匀(36%)、均匀(9%)、不均匀/环形(6.5%)或混合不均匀/均匀强化(6.5%)。肿块的最长轴呈头尾方向(68%)或背腹方向(32%)。CT计算的中位体积为7.57 cm³。常见特征为肌肉组织明显的局部浸润性以及肿瘤周边组织的不均匀性。当纤维肉瘤位于肩胛间时,除了采用前肢向头侧伸展的标准方案外,在前肢沿身体向尾侧定位的情况下进行额外的增强后扫描,能够更好地评估肿瘤与周围组织之间的实际关系。前肢伸展时,肿瘤累及的肌肉平均数量为2.09块,前肢屈曲时为1.95块。当通过双重定位认为浸润的结构数量较少时,对下方肌肉和肩胛骨采用侵入性较小的手术方法。

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