BMBS, Paediatric Intensive Care Unit, Nottingham Children's Hospital, Queen's Medical Centre, Derby Rd, Nottingham, NG7 2UH United Kingdom.
Pediatrics. 2013 Feb;131(2):e626-8. doi: 10.1542/peds.2012-0587. Epub 2013 Jan 6.
A 23-week-old baby, born at 26(+2) weeks, presented to the hospital with critical respiratory failure, which was impossible to stabilize. She had unstable oxygen saturations between 35% and 95%. A presumptive diagnosis of bronchopulmonary dysplasia with associated pulmonary hypertensive crisis was made. In the absence of inhaled nitric oxide, 2 oral doses of 1 mg/kg sildenafil were given, with a dramatic improvement 30 to 45 minutes later. Her oxygenation index fell from 43 to 14. She made a full recovery and was discharged from the hospital 2 weeks later.
一名 23 周大的婴儿，胎龄 26（+2）周，因严重呼吸衰竭而被送往医院，情况非常危急，无法稳定下来。她的血氧饱和度在 35%至 95%之间不稳定。初步诊断为支气管肺发育不良伴相关肺动脉高压危象。在没有吸入一氧化氮的情况下，给予了 2 次 1mg/kg 的口服西地那非，30 至 45 分钟后病情显著改善。她的氧合指数从 43 降至 14。她完全康复，两周后出院。
