The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1488-93. doi: 10.1073/pnas.1221398110. Epub 2013 Jan 7.
The number of neurons under a square millimeter of cortical surface has been reported to be the same across five cortical areas and five species [Rockel et al. (1980) Brain 103(2):221-244] despite differences in cortical thickness between the areas. Although the accuracy of this result has been the subject of sharp debate since its publication approximately 30 y ago, the experiments of Rockel et al. have never been directly replicated with modern stereological methods. We have replicated these experiments and confirm the accuracy of the original report. In addition, we have observed that the number of glial cells under a square millimeter of cortical surface depends on cortical thickness, but not on cortical area or species.
据报道，尽管不同脑区的皮层厚度存在差异，但在五个脑区和五个物种中，每平方毫米皮层表面下的神经元数量是相同的[Rockel 等人，（1980）《大脑》103（2）：221-244]。尽管自大约 30 年前该研究结果发表以来，人们对这一结果的准确性一直存在激烈的争论，但 Rockel 等人的实验从未使用现代体视学方法直接复制。我们已经复制了这些实验，并证实了原始报告的准确性。此外，我们还观察到，每平方毫米皮层表面下的神经胶质细胞数量取决于皮层厚度，而与皮层区域或物种无关。
