Dipartimento di Chimica, Università di Roma 'La Sapienza', Piazzale Aldo Moro 5, 00185, Roma, Italy.
Nat Prod Res. 2013 Aug;27(15):1413-6. doi: 10.1080/14786419.2012.746342. Epub 2013 Jan 9.
The phytochemical study of the polar fraction of Bellardia trixago (L.) All. led to the isolation of eight iridoid glucosides. Five of these glucosides (aucubin (1), bartsioside (2), melampyroside (3), mussaenoside (4) and gardoside methyl ester (5)) were confirmed as they were previously isolated from this plant, and the remaining three known compounds (mussaenosidic acid (6), geniposidic acid (7) and 8-epiloganin (8)) were isolated here for the first time. Of particular interest were the presence of 7 and 8 due to two reasons: the first one because it is not accompanied with geniposide, the corresponding methyl ester, as in the case of 4 and 6, and the second one because it is the parent compound of iridoids characteristic of Orobanchaceae family. Also an alditol, D-mannitol (9), was recognised for the first time from this species.
对琉璃繁缕（Bellardia trixago（L.）All.）极性部分的植物化学研究导致分离出八种裂环环烯醚萜苷。其中 5 种苷（桃叶珊瑚苷（1）、巴尔地山桃草苷（2）、马鞭草苷（3）、毛瑞香苷（4）和Gardoside 甲酯（5））已被证实为先前从该植物中分离出的化合物，而其余 3 种已知化合物（毛瑞香酸（6）、京尼平酸（7）和 8-表告依春（8））则为首次从该植物中分离得到。7 和 8 的存在特别值得关注，原因有两个：第一个原因是，它不像 4 和 6 那样与相应的甲酯京尼平苷一起存在；第二个原因是，它是特征性的玄参科裂环环烯醚萜苷的母体化合物。此外，还首次从该物种中鉴定出糖醇 D-甘露醇（9）。
