Department of Neuropsychology, Kennedy Krieger Institute, Baltimore, MD 21231, USA.
J Int Neuropsychol Soc. 2013 Feb;19(2):189-97. doi: 10.1017/S1355617712001191. Epub 2013 Jan 8.
Impairments in adaptive functioning are frequently associated with intellectual disability (ID); however, adaptive dysfunction can be seen in many individuals with a variety of neurological conditions without ID. The extent to which other variables may be associated with adaptive dysfunction is unclear. In a mixed clinical sample of children (n = 348) consecutively referred for neuropsychological evaluation, the majority were rated as showing weak adaptive skills (ABAS-II, >1 SD below the mean; 71%), with a substantial proportion evidencing frank impairment (>2 SD below the mean, 45%). We examined patterns of scores on measures of intelligence (WISC-IV) and behavioral/affective dysregulation (BRIEF and BASC-2). Using hierarchical cluster analysis, a four cluster model yielded the most appropriate fit and adaptive functioning was subsequently examined across clusters. As expected, adaptive functioning was most intact in the cluster characterized by average IQ and minimal behavioral dysregulation. Other clusters were marked by adaptive dysfunction and distinguished by sub-average intellectual functioning and varying behavioral/emotional dysregulation. In contrast to traditional views associating low IQ with adaptive dysfunction, adaptive impairment was comparable between the cluster characterized by low intelligence and the cluster with average intelligence but significant behavioral dysregulation. These data suggest that adaptive functioning should be considered across various cognitive/behavioral conditions.
适应功能障碍常与智力障碍(ID)相关;然而,在许多无智力障碍的神经疾病患者中也可观察到适应功能障碍。其他变量与适应功能障碍的关联程度尚不清楚。在连续接受神经心理评估的混合临床儿童样本(n=348)中,大多数被评定为具有较弱的适应技能(ABAS-II,低于平均值 1 个标准差以上;71%),相当大的比例存在明显的损伤(低于平均值 2 个标准差以上,45%)。我们检查了智力(WISC-IV)和行为/情感失调(BRIEF 和 BASC-2)测量的得分模式。使用分层聚类分析,四聚类模型产生了最合适的拟合,随后在聚类之间检查了适应功能。如预期的那样,以平均智商和最小行为失调为特征的聚类中的适应功能最完整。其他聚类以适应功能障碍为特征,其特点是智力低于平均水平,以及不同程度的行为/情绪失调。与将低智商与适应功能障碍相关联的传统观点相反,在以低智商为特征的聚类和以平均智商但显著行为失调为特征的聚类中,适应损伤相当。这些数据表明,应在各种认知/行为情况下考虑适应功能。