Vara-Thorbeck R, Guerrero J A, Rosell J, Ruiz-Morales M, Tovar J L, Morales O I
Chirurgische Universitätsklinik, der Medizinischen Fakultät Granada, Spanien.
Langenbecks Arch Chir. 1990;375(2):71-5. doi: 10.1007/BF00713389.
In the University Hospital of Granada (Spain), 359 surgical trauma patients underwent intraoperative autotransfusion. The patients were divided into 2 groups, according to their blood loss: group I (blood loss less than or equal to 2000 ml) and group II (blood loss greater than 2000 ml). Patients from group I did not require homologous blood transfusion. So the high risk involved in this type of transfusion was avoided. Macroscopic haemoglobinuria was only found in those patients where the Solcotrans, Viavae type of autotransfusion system was used; with the Bentley ATS system, no macroscopic haemoglobinuria was registered. With patients from group II, however, that is, those with a blood loss of more than 2000 ml, we had to fall back on homologous transfusion in addition to retransfusing autologous blood. When the transfusion exceeds 4000 ml there is increasing bleeding, which requires treatment with fresh frozen plasma, platelets and/or fibrinogen. The mortality rate of patients in group II was very high but the patients died from the severity of their injuries or from postoperative complications which were not due to autotransfusion in itself with the exception of 3 patients who underwent massive autotransfusion (12,000 to 25,000 ml) and died from acute renal failure. The main indication for intraoperative autotransfusion is without doubt abdominal and thoracic trauma which lead to high blood loss.
在西班牙格拉纳达大学医院,359例外科创伤患者接受了术中自体输血。根据失血量,患者被分为两组:第一组(失血量小于或等于2000毫升)和第二组(失血量大于2000毫升)。第一组患者不需要输注异体血。因此避免了此类输血所涉及的高风险。仅在使用Solcotrans Viavae型自体输血系统的患者中发现了肉眼可见的血红蛋白尿;使用Bentley ATS系统时,未记录到肉眼可见的血红蛋白尿。然而,对于第二组患者,即失血量超过2000毫升的患者,除了回输自体血外,我们还不得不依赖异体输血。当输血量超过4000毫升时,出血会增加,这需要用新鲜冰冻血浆、血小板和/或纤维蛋白原进行治疗。第二组患者的死亡率非常高,但患者死于损伤的严重程度或术后并发症,这些并发症并非由自体输血本身导致,只有3例接受大量自体输血(12000至25000毫升)的患者死于急性肾衰竭。术中自体输血的主要适应证无疑是导致大量失血的腹部和胸部创伤。