UQ Centre for Clinical Research, The University of Queensland, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.
Eur J Clin Nutr. 2013 Jan;67 Suppl 1:S28-33. doi: 10.1038/ejcn.2012.162.
BACKGROUND/OBJECTIVES: There is a critical need for improved technologies to monitor fluid balance and body composition in neonates, particularly those receiving intensive care. Bioelectrical impedance analysis meets many of the criteria required in this environment and appears to be effective for monitoring physiological trends.
SUBJECT/METHODS: The literature regarding the use of bioelectrical impedance in neonates was reviewed.
It was found that prediction equations for total body water, extracellular water and fat-free mass have been developed, but many require further testing and validation in larger cohorts. Alternative approaches based on Hanai mixture theory or vector analysis are in the early stages of investigation in neonates.
Further research is required into electrode positioning, bioimpedance spectroscopy and Cole analysis in order to realise the full potential of this technology.
背景/目的：急需改进的技术来监测新生儿的液体平衡和身体成分，特别是那些接受重症监护的新生儿。生物电阻抗分析满足了该环境中所需的许多标准，并且似乎对监测生理趋势有效。
方法/方法：回顾了有关生物电阻抗在新生儿中应用的文献。
已经发现，已经开发出了用于总水量、细胞外液和去脂体重的预测方程，但许多方程需要在更大的队列中进行进一步的测试和验证。基于 Hanai 混合理论或向量分析的替代方法仍处于在新生儿中进行早期研究阶段。
需要进一步研究电极定位、生物阻抗光谱和 Cole 分析，以充分发挥这项技术的潜力。
