Division of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health, Houston, TX, USA,
J Immigr Minor Health. 2013 Aug;15(4):836-41. doi: 10.1007/s10903-012-9770-8.
While Hispanics in the U.S. are a population with significant within-group heterogeneity, epidemiologic studies often aggregate Hispanics into one homogenous group without considering differences by nativity. The objective of this study is to evaluate nativity differences in the risk behavior profile associated with prevalent high risk human papillomavirus (HR-HPV) among U.S.- and foreign-born Hispanic women. Using a clinical trial dataset, we compare risk behavior and HR-HPV infection patterns among U.S.- and foreign-born participants and assess factors associated with infection in each group. While the prevalence of HR-HPV infection was similar among U.S.- and foreign-born participants, U.S.-born cases had a higher HR-HPV risk profile. The similar prevalence of HR-HPV despite foreign-born women's lower risk profile suggests a role for unmeasured risk factors among foreign-born Hispanics. More importantly, nativity differences in behavioral risk factors associated with HR-HPV suggest the need to further research cervical cancer risk factors among disaggregated Hispanic subgroups.
在美国，西班牙裔人群具有显著的群体内异质性，但流行病学研究通常将西班牙裔人群归为一个同质群体，而不考虑其出生地点的差异。本研究旨在评估与美国和外国出生的西班牙裔女性中普遍存在的高危型人乳头瘤病毒（HR-HPV）相关的风险行为特征的出生地点差异。本研究使用临床试验数据集，比较了美国和外国出生的参与者的风险行为和 HR-HPV 感染模式，并评估了每组感染相关的因素。虽然美国和外国出生的参与者的 HR-HPV 感染率相似，但美国出生的病例具有更高的 HR-HPV 风险特征。尽管外国出生的女性风险特征较低，但 HR-HPV 的相似流行率表明，外国出生的西班牙裔人群中存在未测量的风险因素。更重要的是，与 HR-HPV 相关的行为风险因素的出生地点差异表明，需要进一步研究不同西班牙裔亚组的宫颈癌风险因素。
