精神分裂症患者辅助高频小脑蚓部重复经颅磁刺激治疗后出现听觉言语性幻听恶化:病例报告。
Exacerbation of auditory verbal hallucinations with adjunctive high-frequency cerebellar vermal repetitive transcranial magnetic stimulation in schizophrenia: a case report.
机构信息
Centre for Cognitive Neurosciences and Department of Psychiatry, Central Institute of Psychiatry, Kanke, Ranchi, Jharkhand, India.
出版信息
J ECT. 2013 Mar;29(1):65-6. doi: 10.1097/YCT.0b013e3182706aa1.
In schizophrenia, novel target sites for repetitive transcranial magnetic stimulation (rTMS), such as the cerebellum, are proposed to have a putative therapeutic role in treatment-resistant cases. We present a case of treatment-resistant schizophrenia that showed worsening of auditory verbal hallucinations after receiving high-frequency cerebellar vermal rTMS. We propose that cerebellar vermal rTMS modulates neuronal networks, causing activation in temporoparietal areas, which results in worsening of auditory verbal hallucinations.
在精神分裂症中,提议将重复经颅磁刺激(rTMS)的新靶标部位,如小脑,用于治疗抵抗病例,具有潜在的治疗作用。我们介绍了一例治疗抵抗性精神分裂症的病例,该患者在接受高频小脑蚓部 rTMS 治疗后出现了听觉言语幻觉加重的情况。我们提出,小脑蚓部 rTMS 调节神经元网络,导致颞顶叶区域的激活,从而导致听觉言语幻觉加重。